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Lortz, Stephan [Author]

Die Bedeutung zytoprotektiver Enzyme für den Schutz insulinproduzierender Zellen gegenüber einer Schädigung durch Sauerstoffradikale, NO und Zytokine - [published Version]

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Hannover : Universität, 1999
Vidrio Huerta, Brenda Esmeralda [Author] ; Lortz, Stephan [Degree supervisor]; Knudsen, Lars [Degree supervisor]; Fiedler, Jan [Degree supervisor] Medizinische Hochschule Hannover, Hannover Biomedical Research School, Hannover Biomedical Research School, Medizinische Hochschule Hannover Institut für Klinische Biochemie, Medizinische Hochschule Hannover Institut für Klinische Biochemie

Elevated insulin biosynthesis and folding in the initial course of type 2 diabetes causing β-cell damage by luminal H2O2 generation and oxidative ER stress

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Hannover, April 2021
Vidrio Huerta, Brenda Esmeralda [Author] ; Lortz, Stephan [Degree supervisor]; Knudsen, Lars [Degree supervisor]; Fiedler, Jan [Degree supervisor] Hannover Biomedical Research School, Institut für Klinische Biochemie

Elevated insulin biosynthesis and folding in the initial course of type 2 diabetes causing β-cell damage by luminal H2O2 generation and oxidative ER stress

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Hannover: Bibliothek der Medizinischen Hochschule Hannover, 2021
Mehmeti, Ilir; Lortz, Stephan; Lenzen, Sigurd

The H2O2-sensitive HyPer protein targeted to the endoplasmic reticulum as a mirror of the oxidizing thiol–disulfide milieu

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Elsevier BV, 2012

Published in: Free Radical Biology and Medicine, 53 (2012) 7, Seite 1451-1458
Lenzen, Sigurd; Lortz, Stephan; Tiedge, Markus

Effects of metformin on SGLT1, GLUT2, and GLUT5 hexose transporter gene expression in small intestine from rats

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Elsevier BV, 1996

Published in: Biochemical Pharmacology, 51 (1996) 7, Seite 893-896
Sharifi, Sarah; Böger, Maren; Lortz, Stephan; Mehmeti, Ilir

Luminal H 2 O 2 promotes ER Ca 2+ dysregulation and toxicity of palmitate in insulin‐secreting INS‐1E cells

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Wiley, 2023

Published in: The FASEB Journal, 37 (2023) 1
Laporte, Anna; Lortz, Stephan; Schaal, Christina; Lenzen, Sigurd; Elsner, Matthias

Hydrogen peroxide permeability of cellular membranes in insulin-producing cells

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Elsevier BV, 2020

Published in: Biochimica et Biophysica Acta (BBA) - Biomembranes, 1862 (2020) 2, Seite 183096
Mehmeti, Ilir; Lortz, Stephan; Elsner, Matthias; Lenzen, Sigurd

Peroxiredoxin 4 Improves Insulin Biosynthesis and Glucose-induced Insulin Secretion in Insulin-secreting INS-1E Cells

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Elsevier BV, 2014

Published in: Journal of Biological Chemistry, 289 (2014) 39, Seite 26904-26913
Gurgul-Convey, Ewa; Mehmeti, Ilir; Lortz, Stephan; Lenzen, Sigurd

Cytokine toxicity in insulin-producing cells is mediated by nitro-oxidative stress-induced hydroxyl radical formation in mitochondria

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Springer Science and Business Media LLC, 2011

Published in: Journal of Molecular Medicine, 89 (2011) 8, Seite 785-798
Mehmeti, Ilir; Gurgul-Convey, Ewa; Lenzen, Sigurd; Lortz, Stephan

Induction of the intrinsic apoptosis pathway in insulin-secreting cells is dependent on oxidative damage of mitochondria but independent of caspase-12 activation

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Elsevier BV, 2011

Published in: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1813 (2011) 10, Seite 1827-1835
Ximenes, Helena M.; Lortz, Stephan; Jörns, Anne; Lenzen, Sigurd

Triiodothyronine (T3)-mediated toxicity and induction of apoptosis in insulin-producing INS-1 cells

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Elsevier BV, 2007

Published in: Life Sciences, 80 (2007) 22, Seite 2045-2050
Gurgul, Ewa; Lortz, Stephan; Tiedge, Markus; Jörns, Anne; Lenzen, Sigurd

Mitochondrial Catalase Overexpression Protects Insulin-Producing Cells Against Toxicity of Reactive Oxygen Species and Proinflammatory Cytokines

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American Diabetes Association, 2004

Published in: Diabetes, 53 (2004) 9, Seite 2271-2280
Tiedge, Markus; Lortz, Stephan; Drinkgern, Jens; Lenzen, Sigurd

Relation Between Antioxidant Enzyme Gene Expression and Antioxidative Defense Status of Insulin-Producing Cells

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American Diabetes Association, 1997

Published in: Diabetes, 46 (1997) 11, Seite 1733-1742
Azevedo-Martins, Anna Karenina; Lortz, Stephan; Lenzen, Sigurd; Curi, Rui; Eizirik, Decio L.; Tiedge, Markus

Improvement of the Mitochondrial Antioxidant Defense Status Prevents Cytokine-Induced Nuclear Factor-κB Activation in Insulin-Producing Cells

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American Diabetes Association, 2003

Published in: Diabetes, 52 (2003) 1, Seite 93-101
Melo, Eduardo Pinho; Lopes, Carlos; Gollwitzer, Peter; Lortz, Stephan; Lenzen, Sigurd; Mehmeti, Ilir; Kaminski, Clemens F.; Ron, David; Avezov, Edward

TriPer, an optical probe tuned to the endoplasmic reticulum tracks changes in luminal H2O2

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Springer Science and Business Media LLC, 2017

Published in: BMC Biology, 15 (2017) 1
Gomes, Vinícius M.; Wailemann, Rosangela A. M.; Arini, Gabriel S.; Oliveira, Talita C.; Almeida, Daria R. Q.; dos Santos, Ancély F.; Terra, Letícia F.; Lortz, Stephan; Labriola, Leticia

HSPB1 Is Essential for Inducing Resistance to Proteotoxic Stress in Beta-Cells

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MDPI AG, 2021

Published in: Cells, 10 (2021) 9, Seite 2178
Küster, D.; Kaufhold, Stephan; Limam, Emanetoullah; Jatlaoui, Omar; Ba, Oumar; Mohamed, Abdellahi Maham Zein; Pohlmann-Lortz, M.; Ranneberg, M.; Ufer, K.

Investigation of unexplored kaolin occurrences in southern Mauritania and preliminary assessment of possible applications

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Mineralogical Society, 2021

Published in: Clay Minerals, 56 (2021) 2, Seite 126-139
Dingerkus, Vita L. S.; Munk, Marion R.; Brinkmann, Max P.; Freiberg, Florentina J.; Heussen, Florian M. A.; Kinzl, Stephan; Lortz, Sandra; Orgül, Selim; Becker, Matthias

Optical coherence tomography angiography (OCTA) as a new diagnostic tool in uveitis

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Springer Science and Business Media LLC, 2019

Published in: Journal of Ophthalmic Inflammation and Infection, 9 (2019) 1
Eugène, Marc; Duchnowski, Piotr; Prendergast, Bernard; Wendler, Olaf; Laroche, Cécile; Monin, Jean-Luc; Jobic, Yannick; Popescu, Bogdan A.; Bax, Jeroen J.; Vahanian, Alec; Iung, Bernard; Iung, Bernard; Bax, Jeroen; De Bonis, Michele; Delgado, Victoria; Haude, Michael; Hindricks, Gerhard; Maggioni, Aldo P.; Pierard, Luc; Popescu, Bogdan A.; Prendergast, Bernard; Price, Susanna; Rosenhek, Raphael; Ruschitzka, Frank; [...]

Contemporary Management of Severe Symptomatic Aortic Stenosis

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Elsevier BV, 2021

Published in: Journal of the American College of Cardiology, 78 (2021) 22, Seite 2131-2143

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