Skip to contents

  1. Peters, Femke P.; Teo, Mark T.W.; Appelt, Ane L.; Bach, Simon; Baatrup, Gunnar; de Wilt, Johannes H.W.; Jensenius Kronborg, Camilla; Garm Spindler, Karen-Lise; Marijnen, Corrie A.M.; Sebag-Montefiore, David

    Mesorectal radiotherapy for early stage rectal cancer: A novel target volume

    Articles
    View online
    Close

    Bookmarks

    You can manage bookmarks using lists, please log in to your user account for this.

    Elsevier BV, 2020

    Published in: Clinical and Translational Radiation Oncology, 21 (2020), Seite 104-111

  2. Gollins, Simon; West, Nicholas; Sebag-Montefiore, David; Susnerwala, Shabbir; Falk, Stephen; Brown, Nick; Saunders, Mark; Quirke, Philip; Ray, Ruby; Parsons, Philip; Griffiths, Gareth; Maughan, Tim; Adams, Richard; Hurt, Chris

    A prospective phase II study of pre-operative chemotherapy then short-course radiotherapy for high risk rectal cancer: COPERNICUS

    Articles
    View online
    Close

    Bookmarks

    You can manage bookmarks using lists, please log in to your user account for this.

    Springer Science and Business Media LLC, 2018

    Published in: British Journal of Cancer, 119 (2018) 6, Seite 697-706

  3. Mukherjee, Somnath; Hurt, Chris; Gwynne, Sarah; Bateman, Andrew; Gollins, Simon; Radhakrishna, Ganesh; Canham, Jo; Ray, Ruby; Grabsch, Heike I; Sharma, Ricky A.; Maggs, Rhydian; Hawkins, Maria A; Sebag-Montefiore, David; Maughan, Tim; Griffiths, Gareth; Crosby, Tom David Lewis

    NEOSCOPE: A randomised Phase II study of induction chemotherapy followed by either oxaliplatin/capecitabine (OXCAP) or carboplatin/paclitaxel (CarPac) based chemoradiation (CRT) as pre-operative regimen for resectable oesophageal adenocarcinoma

    Articles
    View online
    Close

    Bookmarks

    You can manage bookmarks using lists, please log in to your user account for this.

    American Society of Clinical Oncology (ASCO), 2016

    Published in: Journal of Clinical Oncology, 34 (2016) 4_suppl, Seite 3-3

  4. Gollins, Simon; Quirke, Philip; Myint, Sun; Saunders, Mark P.; Sebag-Montefiore, David; Susnerwala, Shabbir; Essapen, Sharadah; Samuel, Leslie M.; Sizer, Bruce; Beare, Sandy; Emma, Lawrie; Jitlal, Mark; West, Nicholas

    Pretreatment and postresection epidermal growth factor receptor (EGFR) pathway mutations in a prospective phase II trial (EXCITE) of preoperative cetuximab-containing chemoradiation (CRT) in locally advanced rectal cancer (LARC)

    Articles
    View online
    Close

    Bookmarks

    You can manage bookmarks using lists, please log in to your user account for this.

    American Society of Clinical Oncology (ASCO), 2014

    Published in: Journal of Clinical Oncology, 32 (2014) 3_suppl, Seite 458-458

  5. Mahmood, Umair; Blake, Andrew; Rathee, Sanjay; Samuel, Leslie; Murray, Graeme; Sebag-Montefiore, David; Gollins, Simon; West, Nicholas P.; Begum, Rubina; Bach, Simon P.; Richman, Susan D.; Quirke, Phil; Redmond, Keara L.; Salto-Tellez, Manuel; Koelzer, Viktor H.; Leedham, Simon J.; Tomlinson, Ian; Dunne, Philip D.; Buffa, Francesca M.; Maughan, Tim S.; Domingo, Enric

    Stratification to Neoadjuvant Radiotherapy in Rectal Cancer by Regimen and Transcriptional Signatures

    Articles
    View online
    Close

    Bookmarks

    You can manage bookmarks using lists, please log in to your user account for this.

    American Association for Cancer Research (AACR), 2024

    Published in: Cancer Research Communications, 4 (2024) 7, Seite 1765-1776

  6. Domingo, Enric; Rathee, Sanjay; Blake, Andrew; Samuel, Leslie; Murray, Graeme; Sebag-Montefiore, David; Gollins, Simon; West, Nick P.; Begum, Rubina; Richman, Susan; Quirke, Philip; Redman, Keara; Chatzpili, Aikaterini; Barberis, Alessandro; Hassanieh, sylvana; Mahmoud, Umair; Youdell, Michael; mcdermot, ultan; Koelzer, Viktor H.; Leedham, Simon; Dunne, Philip; Tomlinson, Ian; Buffa, Francesca; Maughan, Tim;

    A Machine Learning Model of Complete Response to Radiation in Rectal Cancer Reveals Immune Infiltrate and TGFβ Signalling as Key Predictors

    Articles
    View online
    Close

    Bookmarks

    You can manage bookmarks using lists, please log in to your user account for this.

    Elsevier BV, 2022

    Published in: SSRN Electronic Journal (2022)

  7. Hudson, Eleanor M; Noutch, Samantha; Brown, Sarah; Adapala, Ravi; Bach, Simon P; Burnett, Carole; Burrage, Alwyn; Gilbert, Alexandra; Hawkins, Maria; Howard, Debra; Jefford, Monica; Kochhar, Rohit; Saunders, Mark; Seligmann, Jenny; Smith, Alexandra; Teo, Mark; Webb, Edward JD; Webster, Amanda; West, Nicholas; Sebag-Montefiore, David; Gollins, Simon; Appelt, Ane L

    A Phase II trial of Higher RadiOtherapy Dose In The Eradication of early rectal cancer (APHRODITE): protocol for a multicentre, open-label randomised controlled trial

    Articles
    View online
    Close

    Bookmarks

    You can manage bookmarks using lists, please log in to your user account for this.

    BMJ, 2022

    Published in: BMJ Open, 12 (2022) 4, Seite e049119

  8. Sebag-Montefiore, David; Adams, Richard; Gollins, Simon; Samuel, Leslie M.; Glynne-Jones, Robert; Harte, Robert; West, Nicholas; Quirke, Philip; Myint, Arthur Sun; Bach, Simon P; Parsons, Philip; Falk, Stephen; Dhadda, Amandeep Singh; Misra, Vivek; Brown, Nick; Brown, Gina; Harrison, Mark; White, Laura; Duggan, Marian; Lopes, Andre

    ARISTOTLE: A phase III trial comparing concurrent capecitabine with capecitabine and irinotecan (Ir) chemoradiation as preoperative treatment for MRI-defined locally advanced rectal cancer (LARC)

    Articles
    View online
    Close

    Bookmarks

    You can manage bookmarks using lists, please log in to your user account for this.

    American Society of Clinical Oncology (ASCO), 2020

    Published in: Journal of Clinical Oncology, 38 (2020) 15_suppl, Seite 4101-4101

  9. Lafarge, Maxime W.; Domingo, Enric; Sirinukunwattana, Korsuk; Wood, Ruby; Samuel, Leslie; Murray, Graeme; Richman, Susan D.; Blake, Andrew; Sebag-Montefiore, David; Gollins, Simon; Klieser, Eckhard; Neureiter, Daniel; Huemer, Florian; Greil, Richard; Dunne, Philip; Quirke, Philip; Weiss, Lukas; Rittscher, Jens; Maughan, Tim; Koelzer, Viktor H.

    Image-based consensus molecular subtyping in rectal cancer biopsies and response to neoadjuvant chemoradiotherapy

    Articles
    View online
    Close

    Bookmarks

    You can manage bookmarks using lists, please log in to your user account for this.

    Springer Science and Business Media LLC, 2024

    Published in: npj Precision Oncology, 8 (2024) 1

  10. Bach, Simon Parkinson; de Wilt, Johannes H.W.; Peters, Femke; Spindler, Karen-Lise Garm; Appelt, Ane L; Teo, Mark; Homer, Victoria; Abbott, Natalie Louise; Geh, Ian; Korsgen, Stephan; Al-Najami, Issam; Rombouts, Anouk J.M.; Christensen, Peter; Gilbert, Alexandra; Navarro-Nuñez, Leyre; Quirke, Philip; West, Nicholas; Baatrup, Gunnar; Marijnen, Corrie; Sebag-Montefiore, David

    STAR-TREC phase II: Can we save the rectum by watchful waiting or transanal surgery following (chemo)radiotherapy versus total mesorectal excision for early rectal cancer?

    Articles
    View online
    Close

    Bookmarks

    You can manage bookmarks using lists, please log in to your user account for this.

    American Society of Clinical Oncology (ASCO), 2022

    Published in: Journal of Clinical Oncology, 40 (2022) 16_suppl, Seite 3502-3502

  11. Domingo, Enric; Rathee, Sanjay; Blake, Andrew; Samuel, Leslie M.; Murray, Graeme I.; Sebag-Montefiore, David; Gollins, Simon; West, Nicholas; Begum, Rubina; Duggan, Marian; White, Laura; Richman, Susan; Quirke, Philip; Robineau, James; Redmond, Keara; Chatzipli, Aikaterini; McDermott, Ultan; Tomlinson, Ian; Dunne, Philip; Buffa, Francesca; Maughan, Tim

    Abstract LB129: Stratification of radiotherapy and fluoropyrimidine-based chemotherapy from multi-omic profiling in rectal cancer biopsies

    Articles
    View online
    Close

    Bookmarks

    You can manage bookmarks using lists, please log in to your user account for this.

    American Association for Cancer Research (AACR), 2021

    Published in: Cancer Research, 81 (2021) 13_Supplement, Seite LB129-LB129

  12. Mukherjee, Somnath; Hurt, Chris; Cox, Catrin; Radhakrishna, Ganesh; Gwynne, Sarah; Bateman, Andrew Rea; Gollins, Simon; Hawkins, Maria A.; Canham, Jo; Grabsch, Heike I.; Falk, Stephen; Sharma, Ricky A.; Ray, Ruby; Roy, Rajarshi; Wade, Wendy; Maggs, Rhydian; sebag-Montefiore, David joseph; Maughan, Tim; Griffiths, Gareth Owen; Crosby, Tom David Lewis

    Induction oxaliplatin capecitabine followed by switch to carboplatin-paclitaxel based RT versus continuing oxaliplatin capecitabine RT in operable esophageal adenocarcinoma: Survival analysis of the randomized phase II neoscope trial

    Articles
    View online
    Close

    Bookmarks

    You can manage bookmarks using lists, please log in to your user account for this.

    American Society of Clinical Oncology (ASCO), 2020

    Published in: Journal of Clinical Oncology, 38 (2020) 4_suppl, Seite 373-373

  13. Gollins, Simon; West, Nick; Sebag-Montefiore, David; Myint, Arthur Sun; Saunders, Mark; Susnerwala, Shabbir; Quirke, Phil; Essapen, Sharadah; Samuel, Leslie; Sizer, Bruce; Worlding, Jane; Southward, Katie; Hemmings, Gemma; Tinkler-Hundal, Emma; Taylor, Morag; Bottomley, Daniel; Chambers, Philip; Lawrie, Emma; Lopes, Andre; Beare, Sandy

    Preoperative chemoradiation with capecitabine, irinotecan and cetuximab in rectal cancer: significance of pre-treatment and post-resection RAS mutations

    Articles
    View online
    Close

    Bookmarks

    You can manage bookmarks using lists, please log in to your user account for this.

    Springer Science and Business Media LLC, 2017

    Published in: British Journal of Cancer, 117 (2017) 9, Seite 1286-1294

  14. Mukherjee, Somnath; Hurt, Christopher N; Gwynne, Sarah; Bateman, Andrew; Gollins, Simon; Radhakrishna, Ganesh; Hawkins, Maria; Canham, Jo; Lewis, Wyn; Grabsch, Heike I; Sharma, Ricky A; Wade, Wendy; Maggs, Rhydian; Tranter, Bethan; Roberts, Ashley; Sebag-Montefiore, David; Maughan, Timothy; Griffiths, Gareth; Crosby, Tom

    NEOSCOPE: a randomised Phase II study of induction chemotherapy followed by either oxaliplatin/capecitabine or paclitaxel/carboplatin based chemoradiation as pre-operative regimen for resectable oesophageal adenocarcinoma

    Articles
    View online
    Close

    Bookmarks

    You can manage bookmarks using lists, please log in to your user account for this.

    Springer Science and Business Media LLC, 2015

    Published in: BMC Cancer, 15 (2015) 1

  15. Crosby, Thomas; Mukherjee, Somnath; Hurt, Chris; Gwynne, Sarah; Gollins, Simon; Bateman, Andrew Rea; Lewis, Wyn Griffith; Radhakrishna, Ganesh; Hawkins, Maria; Grabsch, Heike I.; Ray, Ruby; Sharma, Ricky A.; Wade, Wendy; Maggs, Rhydian; Tranter, Bethan; Roberts, Ashley; Hadlow, Sue; Sebag-Montefiore, David; Maughan, Tim; Griffiths, Gareth

    NeoSCOPE: A phase II randomized comparison of neoadjuvant oxaliplatin/capecitabine versus carboplatin/paclitaxel-based chemoradiation in operable esophageal cancer

    Articles
    View online
    Close

    Bookmarks

    You can manage bookmarks using lists, please log in to your user account for this.

    American Society of Clinical Oncology (ASCO), 2014

    Published in: Journal of Clinical Oncology, 32 (2014) 15_suppl, Seite TPS4144-TPS4144

  16. Domingo, Enric; Rathee, Sanjay; Blake, Andrew; Samuel, Leslie; Murray, Graeme; Sebag-Montefiore, David; Gollins, Simon; West, Nicholas; Begum, Rubina; Richman, Susan; Quirke, Phil; Redmond, Keara; Chatzipli, Aikaterini; Barberis, Alessandro; Hassanieh, Sylvana; Mahmood, Umair; Youdell, Michael; McDermott, Ultan; Koelzer, Viktor; Leedham, Simon; Tomlinson, Ian; Dunne, Philip; Blake, Andrew; Buffa, Francesca; [...]

    Identification and validation of a machine learning model of complete response to radiation in rectal cancer reveals immune infiltrate and TGFβ as key predictors

    Articles
    View online
    Close

    Bookmarks

    You can manage bookmarks using lists, please log in to your user account for this.

    Elsevier BV, 2024

    Published in: eBioMedicine, 106 (2024), Seite 105228

  17. Rombouts, Anouk J M; Al-Najami, Issam; Abbott, Natalie L; Appelt, Ane; Baatrup, Gunnar; Bach, Simon; Bhangu, Aneel; Garm Spindler, Karen-Lise; Gray, Richard; Handley, Kelly; Kaur, Manjinder; Kerkhof, Ellen; Kronborg, Camilla Jensenius; Magill, Laura; Marijnen, Corrie A M; Nagtegaal, Iris D; Nyvang, Lars; Peters, Femke P; Pfeiffer, Per; Punt, Cornelis; Quirke, Philip; Sebag-Montefiore, David; Teo, Mark; West, Nick;

    Can weSave the rectum by watchful waiting orTransAnal microsurgery following (chemo)Radiotherapy versusTotal mesorectal excision for earlyREctalCancer (STAR-TREC study)?: protocol for a multicentre, randomised feasibility study

    Articles
    View online
    Close

    Bookmarks

    You can manage bookmarks using lists, please log in to your user account for this.

    BMJ, 2017

    Published in: BMJ Open, 7 (2017) 12, Seite e019474

  18. Ali, S Mohammed; Antoniou, Anthony; Beynon, John; Bhangu, Aneel; Bose, Pradeep; Boyle, Kirsten; Branagan, Graham; Brown, Gina; Burling, David; Chang, George J; Clark, Susan K; Colquhoun, Patrick; Crane, Christopher H; Darzi, Ara; Das, Prajnan; de Wilt, Johannes H W; Delaney, Conor P; Desai, Anant; Davies, Mark; Dietz, David; Dozois, Eric J; Duff, Michael; Dziki, Adam; Fitzgerald, J Edward; [...]

    Consensus statement on the multidisciplinary management of patients with recurrent and primary rectal cancer beyond total mesorectal excision planes

    Articles
    View online
    Close

    Bookmarks

    You can manage bookmarks using lists, please log in to your user account for this.

    Oxford University Press (OUP), 2013

    Published in: British Journal of Surgery, 100 (2013) 8, Seite 1009-1014

  19. Ali, S Mohammed; Antoniou, Anthony; Beynon, John; Bhangu, Aneel; Bose, Pradeep; Boyle, Kirsten; Branagan, Graham; Brown, Gina; Burling, David; Chang, George J; Clark, Susan K; Colquhoun, Patrick; Crane, Christopher H; Darzi, Ara; Das, Prajnan; de Wilt, Johannes H W; Delaney, Conor P; Desai, Anant; Davies, Mark; Dietz, David; Dozois, Eric J; Duff, Michael; Dziki, Adam; Fitzgerald, J Edward; [...]

    Consensus statement on the multidisciplinary management of patients with recurrent and primary rectal cancer beyond total mesorectal excision planes

    Articles
    View online
    Close

    Bookmarks

    You can manage bookmarks using lists, please log in to your user account for this.

    Oxford University Press (OUP), 2013

    Published in: British Journal of Surgery, 100 (2013) 8, Seite E1-E33

  20. Gilbert, Alexandra; Homer, Victoria; Brock, Kristian; Korsgen, Stephan; Geh, Ian; Hill, James; Gill, Talvinder; Hainsworth, Paul; Tutton, Matthew; Khan, Jim; Robinson, Jonathan; Steward, Mark; Cunningham, Christopher; Kaur, Manjinder; Magill, Laura; Russell, Ann; Quirke, Philip; West, Nicholas P; Sebag-Montefiore, David; Bach, Simon P; Beveridge, Alan; Levy, Bruce; Handley, Kelly; Brown, Gina; [...]

    Quality-of-life outcomes in older patients with early-stage rectal cancer receiving organ-preserving treatment with hypofractionated short-course radiotherapy followed by transanal endoscopic microsurgery (TREC): non-randomised registry of patients unsuitable for total mesorectal excision

    Articles
    View online
    Close

    Bookmarks

    You can manage bookmarks using lists, please log in to your user account for this.

    Elsevier BV, 2022

    Published in: The Lancet Healthy Longevity, 3 (2022) 12, Seite e825-e838