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Hamarsheh, Shaima'a [Author]; Osswald, Lena [Author]; Saller, Benedikt S. [Author]; Vinnakota, Janaki Manoja [Author]; Uhl, Franziska [Author]; Becker, Heiko [Author]; Lübbert, Michael [Author]; Shoumariyeh, Khalid [Author]; Geoffroy, Andrieux [Author]; Venhoff, Nils [Author]; Schmitt-Graeff, Annette [Author]; Duquesne, Sandra [Author]; Pfeifer, Dietmar [Author]; Börries, Melanie [Author]; Duyster, Justus [Author]; Niemeyer, Charlotte [Author]; Erlacher, Miriam [Author]; Groß, Olaf [Author]; Brummer, Tilman [Author]; Zeiser, Robert [Author]

Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation

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London: Nature Publishing Group, 2020

Published in: Nature communications ; 11 (2020), 1659
Vinnakota, Janaki Manoja; Zeiser, Robert

Acute Graft-Versus-Host Disease, Infections, Vascular Events and Drug Toxicities Affecting the Central Nervous System

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Frontiers Media SA, 2021

Published in: Frontiers in Immunology, 12 (2021)
Adams, Rachael C.; Carter-Cusack, Dylan; Llanes, Genesis T.; Hunter, Christopher R.; Vinnakota, Janaki Manoja; Ruitenberg, Marc J.; Vukovic, Jana; Bertolino, Patrick; Chand, Kirat K.; Wixey, Julie A.; Nayler, Samuel P.; Hill, Geoffrey R.; Furlan, Scott N.; Zeiser, Robert; MacDonald, Kelli P. A.

CSF1R inhibition promotes neuroinflammation and behavioral deficits during graft-versus-host disease in mice

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American Society of Hematology, 2024

Published in: Blood, 143 (2024) 10, Seite 912-929
Adams, Rachael C; Carter-Cusack, Dylan; Llanes, Genesis T; Hunter, Christopher R; Vinnakota, Janaki Manoja; Ruitenberg, Marc; Vukovic, Jana; Bertolino, Patrick; Chand, Kirat K.; Wixey, Julie A.; Nayler, Samuel P; Hill, Geoffrey R; Furlan, Scott N; Zeiser, Robert; MacDonald, Kelli PA

CSF1R Inhibition Promotes Neuroinflammation and Behavioural Deficits during Graft-Versus-Host Disease in Mice

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American Society of Hematology, 2023

Published in: Blood, 142 (2023) Supplement 1, Seite 2052-2052
Isbell, Lisa Kristina; Tschuch, Cordula; Doostkam, Soroush; Waldeck, Silvia; Andrieux, Geoffroy; Shoumariyeh, Khalid; Lenhard, Dorothee; Schaefer, Hans Eckart; Reinacher, Peter Christoph; Bartsch, Ingrid; Pantic, Milena; Vinnakota, Janaki Manoja; Kakkassery, Vinodh; Schorb, Elisabeth; Scherer, Florian; Frey, Anna Verena; Boerries, Melanie; Illerhaus, Gerald; Duyster, Justus; Schueler, Julia; von Bubnoff, Nikolas

Patient‐derived xenograft mouse models to investigate tropism to the central nervous system and retina of primary and secondary central nervous system lymphoma

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Wiley, 2023

Published in: Neuropathology and Applied Neurobiology, 49 (2023) 2
El Khawanky, Nadia; Hughes, Amy; Yu, Wenbo; Myburgh, Renier; Matschulla, Tony; Taromi, Sanaz; Aumann, Konrad; Clarson, Jade; Vinnakota, Janaki Manoja; Shoumariyeh, Khalid; Miething, Cornelius; Lopez, Angel F.; Brown, Michael P.; Duyster, Justus; Hein, Lutz; Manz, Markus G.; Hughes, Timothy P.; White, Deborah L.; Yong, Agnes S. M.; Zeiser, Robert

Demethylating therapy increases anti-CD123 CAR T cell cytotoxicity against acute myeloid leukemia

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Springer Science and Business Media LLC, 2021

Published in: Nature Communications, 12 (2021) 1
Vinnakota, Janaki Manoja; Adams, Rachael C.; Athanassopoulos, Dimitrios; Schmidt, Dominik; Biavasco, Francesca; Zähringer, Alexander; Erny, Daniel; Schwabenland, Marius; Langenbach, Marlene; Wenger, Valentin; Salié, Henrike; Cook, James; Mossad, Omar; Andrieux, Geoffroy; Dersch, Rick; Rauer, Sebastian; Duquesne, Sandra; Monaco, Gianni; Wolf, Phillipp; Blank, Thomas; Häne, Philipp; Greter, Melanie; Becher, Burkhard; Henneke, Philipp; [...]

Anti–PD-1 cancer immunotherapy induces central nervous system immune-related adverse events by microglia activation

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American Association for the Advancement of Science (AAAS), 2024

Published in: Science Translational Medicine, 16 (2024) 751
Schmidt, Dominik; Endres, Cornelia; Hoefflin, Rouven; Andrieux, Geoffroy; Zwick, Melissa; Karantzelis, Nikolaos; Staehle, Hans F.; Vinnakota, Janaki Manoja; Duquesne, Sandra; Mozaffari Jovein, Miriam; Pfeifer, Dietmar; Becker, Heiko; Blazar, Bruce R.; Zähringer, Alexander; Duyster, Justus; Brummer, Tilman; Boerries, Melanie; Baumeister, Julian; Shoumariyeh, Khalid; Li, Juan; Green, Anthony R.; Heidel, Florian H.; Tirosh, Itay; Pahl, Heike L.; [...]

Oncogenic Calreticulin Induces Immune Escape by Stimulating TGF-β Expression and Regulatory T Cell Expansion in the Bone Marrow Microenvironment

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American Association for Cancer Research (AACR), 2024

Published in: Cancer Research (2024)
Hamarsheh, Shaima’a; Osswald, Lena; Saller, Benedikt S.; Unger, Susanne; De Feo, Donatella; Vinnakota, Janaki Manoja; Konantz, Martina; Uhl, Franziska M.; Becker, Heiko; Lübbert, Michael; Shoumariyeh, Khalid; Schürch, Christoph; Andrieux, Geoffroy; Venhoff, Nils; Schmitt-Graeff, Annette; Duquesne, Sandra; Pfeifer, Dietmar; Cooper, Matthew A.; Lengerke, Claudia; Boerries, Melanie; Duyster, Justus; Niemeyer, Charlotte M.; Erlacher, Miriam; Blazar, Bruce R.; [...]

Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation

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Springer Science and Business Media LLC, 2020

Published in: Nature Communications, 11 (2020) 1
Maas-Bauer, Kristina; Stell, Anna-Verena; Yan, Kai-Li; de Vega, Enrique; Vinnakota, Janaki Manoja; Unger, Susanne; Núñez, Nicolas; Norona, Johana; Talvard-Balland, Nana; Koßmann, Stefanie; Schwan, Carsten; Miething, Cornelius; Martens, Uta S.; Shoumariyeh, Khalid; Nestor, Rosa P.; Duquesne, Sandra; Hanke, Kathrin; Rackiewicz, Michal; Hu, Zehan; El Khawanky, Nadia; Taromi, Sanaz; Andrlova, Hana; Faraidun, Hemin; Walter, Stefanie; [...]

ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease

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Springer Science and Business Media LLC, 2024

Published in: Nature Communications, 15 (2024) 1
Ho, Jenny N. H. G.; Schmidt, Dominik; Lowinus, Theresa; Ryoo, Jeongmin; Dopfer, Elaine-Pashupati; Gonzalo Núñez, Nicolás; Costa-Pereira, Sara; Toffalori, Cristina; Punta, Marco; Fetsch, Viktor; Wertheimer, Tobias; Rittmann, Marie-Claire; Braun, Lukas M.; Follo, Marie; Briere, Christelle; Vinnakota, Janaki Manoja; Langenbach, Marlene; Koppers, Felicitas; Shoumariyeh, Khalid; Engel, Helena; Rückert, Tamina; Märklin, Melanie; Holzmayer, Samuel; Illert, Anna L.; [...]

Targeting MDM2 enhances antileukemia immunity after allogeneic transplantation via MHC-II and TRAIL-R1/2 upregulation

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American Society of Hematology, 2022

Published in: Blood, 140 (2022) 10, Seite 1167-1181
Vinnakota, Janaki Manoja; Biavasco, Francesca; Schwabenland, Marius; Chhatbar, Chintan; Adams, Rachael C; Erny, Daniel; Duquesne, Sandra; El Khawanky, Nadia; Salié, Henrike; Athanassopoulos, Dimitrios; Braun, Lukas; Schmidt, Dominik; Fetsch, Viktor; Javorniczky, Rebeka N.; Ho, Jenny N.H.G; Marks, Reinhard; Wäsch, Ralph; Simonetta, Federico; Andrieux, Geoffroy; Pfeifer, Dietmar; Monaco, Gianni; Capitini, Christian; Fry, Terry J.; Blank, Thomas; [...]

Immune-Effector-Cell-Associated-Neurotoxicity-Syndrome (ICANS) Pathophysiology Is Mediated By Microglia TGF-β-Activated Kinase-1 Signaling

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American Society of Hematology, 2023

Published in: Blood, 142 (2023) Supplement 1, Seite 100-100

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