13th IIS (UK group) symposium

Medientyp: E-Artikel
Titel: 13th IIS (UK group) symposium
Beteiligte: Caddick, Stephen; Stone‐Elander, Sharon; Patching, Simon G.; Herbert, Richard B.; Henderson, Peter J. F.; Brough, Adrian R.; Middleton, David A.; Coumbarides, Gregory S.; Eames, Jason; Ghilagaber, Stephanos; Suggate, Michael J.; Weerasooriya, Neluka; Spivey, Alan C.; Diaper, Chris; Srikaran, Ratnasothy; Jones, Teyrnon; Noban, Catherine; Ellames, George J.; Kohler, Andrew; Wadsworth, Harry; Blagbrough, Ian S.; Ballinger, James R.; Shemilt, Gary; Reid, R Gordon; [...]
Erschienen: Wiley, 2004
Erschienen in: Journal of Labelled Compounds and Radiopharmaceuticals
Sprache: Englisch
DOI: 10.1002/jlcr.819
ISSN: 0362-4803; 1099-1344
Schlagwörter: Organic Chemistry ; Spectroscopy ; Drug Discovery ; Radiology, Nuclear Medicine and imaging ; Biochemistry ; Analytical Chemistry
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Beschreibung: <jats:title>Abstract</jats:title><jats:p>Studies on the chromoprotein antibiotic neocarzinostatin</jats:p><jats:p>The ‘special effects’ of microwaving in radiochemistry.</jats:p><jats:p>Stable isotopes and membrane transport proteins: chemical synthesis and biochemical analysis by solid state NMR</jats:p><jats:p>Synthetic aspects of c‐deuteriation of enolates</jats:p><jats:p>Opportunities for isotope labelling via solid phase synthesis with organogermanium linkers</jats:p><jats:p>Labelled methyllycaconitine (MLA)—a key nicotinic acetylcholine receptor ligand</jats:p><jats:p>Challenges in the preparation of radiolabelled drugs for nuclear medicine</jats:p><jats:p>The synthesis of carbon‐14 labelled PEGs</jats:p><jats:p>Development of palladium catalysed carbonylations for asymmetric synthesis</jats:p><jats:p>The versatility of labelled cyanide</jats:p><jats:p>Poster abstracts on the stability and storage of <jats:sup>14</jats:sup>C‐labelled compounds</jats:p><jats:p>The preparation of the P<jats:sub>2</jats:sub> receptor agonist 2‐[methyl‐<jats:sup>3</jats:sup>H]methylthioadenosine‐5′‐diphosphate</jats:p><jats:p>Tritium labelling of aromatic and aliphatic aldehydes using Crabtree's catalyst, [Ir(cod)py(PCy<jats:sub>3</jats:sub>)]PF<jats:sub>6</jats:sub></jats:p><jats:p>The specific activity determination and confirmation of identity of a radiolabelled peptide using tandem mass spectrometry</jats:p><jats:p>Design and applicatoin of stable or radiolabelled carbamates</jats:p><jats:p>Synthesis of the various isotopomers of the MHC II antagonist AZD2315</jats:p><jats:p>Synthesis of isotopomers of gefitinib</jats:p><jats:p>Mercuration/iododemercuration/deiodination: A practical first‐line strategy for the rapid preparation of iodinated labelling precursors</jats:p><jats:p>Deuterium labelling with cycloocta‐1,5‐dienyliridium(i)1,1,1,5,5,5‐hexafluoropentan‐2,4‐dionate: a comparison of D<jats:sub>2</jats:sub>o and d<jats:sub>2</jats:sub> isotope donors</jats:p><jats:p>Martin D. Kamen (1913‐2002): The co‐discoverer of carbon‐14</jats:p><jats:p>An efficient synthesis of [2‐<jats:sup>14</jats:sup>c] ethyl nipecotate</jats:p><jats:p>Radiosynthesis conducted under cGMP compliance</jats:p><jats:p>Computer‐simulations for the reactor‐synthesis of high‐activity, high specific activity, teletherapy sources of europium‐152</jats:p><jats:p>Parallel optimisation of hydrogen isotope exchange mediated by homogeneous catalysts: A collaboration between the isotope groups at mölndal and charnwood R&D</jats:p><jats:p>New opportunities for isotope labelling using solid phase organic synthesis</jats:p><jats:p>Rapid synthesis of <jats:sup>11</jats:sup>C‐flumazenil in a micro‐reactor placed in the hplc loop: A fast captive solvent method</jats:p><jats:p>Spatiotemporal imaging of receptor systems using pet</jats:p>

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