• Medientyp: E-Artikel
  • Titel: Early Diagnosis of Bladder Exstrophy: Quantitative Assessment of a Low‐Inserted Umbilical Cord
  • Beteiligte: Fishel‐Bartal, Michal; Perlman, Sharon; Messing, Baruch; Bardin, Ron; Kivilevitch, Zvi; Achiron, Reuven; Gilboa, Yinon
  • Erschienen: Wiley, 2017
  • Erschienen in: Journal of Ultrasound in Medicine
  • Umfang: 1801-1805
  • Sprache: Englisch
  • DOI: 10.1002/jum.14212
  • ISSN: 0278-4297; 1550-9613
  • Schlagwörter: Radiology, Nuclear Medicine and imaging ; Radiological and Ultrasound Technology
  • Zusammenfassung: <jats:sec><jats:title>Objectives</jats:title><jats:p>Bladder exstrophy is a rare severe congenital malformation. Early prenatal diagnosis is scarcely described in the literature. Low insertion of the umbilical cord is a constant anatomic feature of bladder exstrophy. The aim of our study was to assess whether early measurements of the umbilical cord insertion–to–genital tubercle length may serve as quantitative measurements for a low‐inserted umbilical cord in cases of bladder exstrophy.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>The umbilical cord insertion–to–genital tubercle length was prospectively measured in all cases referred for a nonvisualized urinary bladder before 18 weeks' gestation. Final diagnoses were compared with prenatal measurements.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Fifteen fetuses were evaluated for a nonvisualized bladder at a mean gestational age of 15.7 weeks (range, 14–17 weeks). Of them, 6 cases were diagnosed with bladder exstrophy, and 9 cases had a normal urinary bladder. All cases with bladder exstrophy had an umbilical cord insertion–to–genital tubercle length below the fifth percentile for gestational age, whereas cases with a normal bladder had a normal measurement.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Fetuses with bladder exstrophy have an umbilical cord insertion–to–genital tubercle length below the fifth percentile of the general population. This measurement may serve as a complementary objective sonographic parameter in the prenatal assessment and counseling of cases suspected of having bladder exstrophy during early pregnancy.</jats:p></jats:sec>
  • Beschreibung: <jats:sec><jats:title>Objectives</jats:title><jats:p>Bladder exstrophy is a rare severe congenital malformation. Early prenatal diagnosis is scarcely described in the literature. Low insertion of the umbilical cord is a constant anatomic feature of bladder exstrophy. The aim of our study was to assess whether early measurements of the umbilical cord insertion–to–genital tubercle length may serve as quantitative measurements for a low‐inserted umbilical cord in cases of bladder exstrophy.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>The umbilical cord insertion–to–genital tubercle length was prospectively measured in all cases referred for a nonvisualized urinary bladder before 18 weeks' gestation. Final diagnoses were compared with prenatal measurements.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Fifteen fetuses were evaluated for a nonvisualized bladder at a mean gestational age of 15.7 weeks (range, 14–17 weeks). Of them, 6 cases were diagnosed with bladder exstrophy, and 9 cases had a normal urinary bladder. All cases with bladder exstrophy had an umbilical cord insertion–to–genital tubercle length below the fifth percentile for gestational age, whereas cases with a normal bladder had a normal measurement.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Fetuses with bladder exstrophy have an umbilical cord insertion–to–genital tubercle length below the fifth percentile of the general population. This measurement may serve as a complementary objective sonographic parameter in the prenatal assessment and counseling of cases suspected of having bladder exstrophy during early pregnancy.</jats:p></jats:sec>
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