• Medientyp: E-Artikel
  • Titel: Antimalarial activity of novel 4-cyano-3-methylisoquinoline inhibitors against Plasmodium falciparum: design, synthesis and biological evaluation
  • Beteiligte: Buskes, Melissa J.; Harvey, Katherine L.; Richards, Benjamin J.; Kalhor, Robabeh; Christoff, Rebecca M.; Gardhi, Chamodi K.; Littler, Dene R.; Cope, Elliott D.; Prinz, Boris; Weiss, Greta E.; O'Brien, Nathan J.; Crabb, Brendan S.; Deady, Leslie W.; Gilson, Paul R.; Abbott, Belinda M.
  • Erschienen: Royal Society of Chemistry (RSC), 2016
  • Sprache: Englisch
  • DOI: 10.1039/c5ob02517f
  • ISSN: 1477-0520; 1477-0539
  • Schlagwörter: Physical and Theoretical Chemistry ; Organic Chemistry ; Biochemistry
  • Zusammenfassung: <p>A series of 4-cyano-3-methylisoquinolines have been shown to inhibit parasite cytokinesis and erythrocyte invasion.</p>