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Medientyp:
E-Artikel
Titel:
Impact of pre-admission depression on mortality following myocardial infarction
Beteiligte:
Sundbøll, Jens;
Schmidt, Morten;
Adelborg, Kasper;
Pedersen, Lars;
Bøtker, Hans Erik;
Videbech, Poul;
Sørensen, Henrik Toft
Erschienen:
Royal College of Psychiatrists, 2017
Erschienen in:
British Journal of Psychiatry, 210 (2017) 5, Seite 356-361
Sprache:
Englisch
DOI:
10.1192/bjp.bp.116.194605
ISSN:
0007-1250;
1472-1465
Entstehung:
Anmerkungen:
Beschreibung:
BackgroundThe prognostic impact of previous depression on myocardial infarction survival remains poorly understood.AimsTo examine the association between depression and all-cause mortality following myocardial infarction.MethodUsing Danish medical registries, we conducted a nationwide population-based cohort study. We included all patients with first-time myocardial infarction (1995–2014) and identified previous depression as either a depression diagnosis or use of antidepressants. We used Cox regression to compute adjusted mortality rate ratios (aMRRs) with 95% confidence intervals.ResultsWe identified 170 771 patients with first-time myocardial infarction. Patients with myocardial infarction and a previous depression diagnosis had higher 19-year mortality risks (87% v. 78%). The overall aMRR was 1.11 (95% CI 1.07–1.15) increasing to 1.22 (95% CI 1.17–1.27) when including use of antidepressants in the depression definition.ConclusionsA history of depression was associated with a moderately increased all-cause mortality following myocardial infarction.