The Primary Structure of Escherichia coli RNA Polymerase : Nucleotide Sequence of the rpoB Gene and Amino‐Acid Sequence of the β‐Subunit

Medientyp: E-Artikel
Titel: The Primary Structure of Escherichia coli RNA Polymerase : Nucleotide Sequence of the rpoB Gene and Amino‐Acid Sequence of the β‐Subunit : Nucleotide Sequence of the <i>rpoB</i> Gene and Amino‐Acid Sequence of the β‐Subunit
Beteiligte: OVCHINNIKOV, Yury A.; MONASTYRSKAYA, Galina S.; GUBANOV, Valentin V.; GURYEV, Sergey O.; CHERTOV, Oleg Yu.; MODYANOV, Nickolay N.; GRINKEVICH, Vladimir A.; MAKAROVA, Irma A.; MARCHENKO, Tatjana V.; POLOVNIKOVA, Irina N.; LIPKIN, Valery M.; SVERDLOV, Eugene D.
Erschienen: Wiley, 1981
Erschienen in: European Journal of Biochemistry
Sprache: Englisch
DOI: 10.1111/j.1432-1033.1981.tb05381.x
ISSN: 0014-2956; 1432-1033
Schlagwörter: Biochemistry
Entstehung:
Anmerkungen:
Beschreibung: <jats:p>The combined structural study of proteins and of their corresponding genes utilizing the methods of both protein and nucleotide chemistry greatly accelerates and considerably simplifies both the nucleotide and protein structure determination and, in particular, enhances the reliability of the analysis. This approach has been successfully applied in the primary structure determination of the β and β′ subunits of <jats:italic>Escherichia coli</jats:italic> DNAdependent RNA polymerise and of their structural genes, yielding a continuous nucleotide, sequence (4714 base pairs) that embraces the entire <jats:italic>rpoB</jats:italic> gene, the initial part of the <jats:italic>rpoC</jats:italic> gene and the intercistronic region, together with the total amino acid sequence of the β subunit, comprising 1342 residues, and the N‐terminal sequence of the β′ subunit (176 residues).</jats:p>
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