• Medientyp: E-Artikel
  • Titel: Successful therapy with ABLC, surgery and posaconazole for Rhizopus microsporus var. rhizopodiformis liver eumycetoma in a child with acute leukaemia
  • Beteiligte: Sedlacek, Petr; Vavra, Vladimir; Masova, Ivana; Codl, Daniel; Laznickova, Tana; Malaskova, Ludmila; Nyc, Otakar; Stary, Jan
  • Erschienen: Wiley, 2009
  • Erschienen in: Mycoses
  • Sprache: Englisch
  • DOI: 10.1111/j.1439-0507.2008.01595.x
  • ISSN: 0933-7407; 1439-0507
  • Schlagwörter: Infectious Diseases ; Dermatology ; General Medicine
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:title>Summary</jats:title><jats:p>Invasive fungal infection negatively influences the morbidity and mortality in heavily immuno‐incompetent patients. Diagnosis of non‐<jats:italic>Aspergillus</jats:italic> mould infections remains challenging despite application of a wide spectrum of non‐culture‐based microbiological techniques. Invasive diagnostic procedures are often essential. In this article, we present the case of a 15‐month‐old boy diagnosed with <jats:italic>Rhizopus microsporus</jats:italic> var. <jats:italic>rhizopodiformis</jats:italic> liver mycetoma during induction chemotherapy for acute promyelocytic leukaemia. Following surgery, he was effectively treated with a combination of ABLC and posaconazole during ongoing intensive chemotherapy. Posaconazole was also used as long‐term secondary prophylaxis.</jats:p>