• Medientyp: E-Artikel
  • Titel: Russian “Successful” Clone B0/W148 of Mycobacterium tuberculosis Beijing Genotype: a Multiplex PCR Assay for Rapid Detection and Global Screening
  • Beteiligte: Mokrousov, Igor; Narvskaya, Olga; Vyazovaya, Anna; Otten, Tatiana; Jiao, Wei-Wei; Gomes, Lia Lima; Suffys, Philip N.; Shen, A-Dong; Vishnevsky, Boris
  • Erschienen in: Journal of Clinical Microbiology
  • Erschienen: American Society for Microbiology, 2012
  • Sprache: Englisch
  • DOI: 10.1128/jcm.02001-12
  • ISSN: 0095-1137; 1098-660X
  • Schlagwörter: Microbiology (medical)
  • Zusammenfassung: <jats:title>ABSTRACT</jats:title> <jats:p> We describe a multiplex PCR assay to detect the <jats:named-content content-type="genus-species">Mycobacterium tuberculosis</jats:named-content> Beijing genotype variant B0/W148, which is considered a “successful” clone of <jats:named-content content-type="genus-species">M. tuberculosis</jats:named-content> , widespread in Russia. Specificity and sensitivity of the assay were 100% based on the analysis of a collection of 516 <jats:named-content content-type="genus-species">M. tuberculosis</jats:named-content> isolates of different genotypes and origins. This assay may be used for accurate and simple detection and surveillance of this clinically and epidemiologically important variant of <jats:named-content content-type="genus-species">M. tuberculosis</jats:named-content> . </jats:p>
  • Beschreibung: <jats:title>ABSTRACT</jats:title>
    <jats:p>
    We describe a multiplex PCR assay to detect the
    <jats:named-content content-type="genus-species">Mycobacterium tuberculosis</jats:named-content>
    Beijing genotype variant B0/W148, which is considered a “successful” clone of
    <jats:named-content content-type="genus-species">M. tuberculosis</jats:named-content>
    , widespread in Russia. Specificity and sensitivity of the assay were 100% based on the analysis of a collection of 516
    <jats:named-content content-type="genus-species">M. tuberculosis</jats:named-content>
    isolates of different genotypes and origins. This assay may be used for accurate and simple detection and surveillance of this clinically and epidemiologically important variant of
    <jats:named-content content-type="genus-species">M. tuberculosis</jats:named-content>
    .
    </jats:p>
  • Anmerkungen:
  • Zugangsstatus: Freier Zugang