• Medientyp: E-Artikel
  • Titel: The use of autologous conditioned plasma (ACP) in the surgical treatment of full-thikness macular holes
  • Beteiligte: Laskova, I.V.; Kravchenko, A.A.; Uskov, D.I.; Lopina, E.V.
  • Erschienen: Publishing House Ophthalmology, 2021
  • Erschienen in: Modern technologies in ophtalmology (2021) 3, Seite 102-105
  • Sprache: Nicht zu entscheiden
  • DOI: 10.25276/2312-4911-2021-3-102-105
  • ISSN: 2312-4911
  • Schlagwörter: Polymers and Plastics ; General Environmental Science
  • Entstehung:
  • Anmerkungen:
  • Beschreibung: <jats:p>Increasingly, the use of autologous conditioned plasma in ophthalmic surgery in recent years has been given more preference than other blood products with similar effects. Surgical treatment of full-thikness macular hole is no exception. Domestic and foreign studies of recent years show that the use of ACP as an adhesive component in the treatment of this pathology is considered the most acceptable. However, in addition to the effective "gluing" of the macular hole, the convergence of its edges plays an important role in the postoperative anatomy of the foveolar zone. Objective: to study the effectiveness of the use of autologous conditioned plasma in the surgical treatment of full-thikness macular hole. Materials and methods of research. Patients who underwent surgery for a full-thikness macular hole with a diameter of more than 400 microns were prospectively observed. The study included 51 patients. The follow-up period ranged from 2 months to 1 year. All patients in the preoperative and postoperative periods underwent a comprehensive ophthalmological examination. Surgical technique: after a standard three-port vitrectomy (25Ga), the posterior hyaloid membrane was removed, and the ILM was peeled. With the help of a saline solution, a circular separation of the bonds between the edges of the gap and the pigment epithelium was achieved. After the subretinal fluid was removed and the induced local central retinal detachment was attached, the tear area was irrigated by ACP. After that, the air was replaced with silicone oil, which was removed after 1.5 months. Nodal sutures were applied to the sclerotomy (vicryl 8-0). Results. In 49 operated patients, anatomical restoration of the foveolar zone was achieved, which accounted for 96% of the total number of patients. Visual functions were evaluated after 1.5 months (after removal of silicone oil). Corrected visual acuity in 96% of patients ranged from 0.2 to 0.5. Conclusion. The high efficiency of the use of autologous conditioned plasma in the treatment of full-thikness macular holes allows us to achieve high anatomical and functional results. Key words: macular rupture, autologous conditioned plasma, silicone tamponade.</jats:p>