Beschreibung:
<jats:title>Abstract</jats:title>
<jats:p>Properdin Factor B shows genetic polymorphism in the human and the polymorphic patterns in agarose gel electrophoresis suggest a tetrameric structure. Factor B polymorphism in the rhesus monkey has been demonstrated in the present study to be genetically determined and under the control of a single autosomal locus, rhesus Bf.</jats:p>
<jats:p>Six codominant alleles, BfF, BfG 1, BfG 2, BfS, BfS 1, BfS 2 have been recognized and the first five have been shown to have gene frequencies of 0.307, 0.160, 0.016, 0.377, and 0.139. The electrophoretic appearance of the polymorphic patterns does not suggest a tetrameric structure in the rhesus. Structural studies show purified human factor B to exist as a single subunit of molecular weight 94,000 daltons so that a tetrameric structure appears highly unlikely.</jats:p>