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Taylor, Peter N.; Porcu, Eleonora; Chew, Shelby; Campbell, Purdey J.; Traglia, Michela; Brown, Suzanne J.; Mullin, Benjamin H.; Shihab, Hashem A.; Min, Josine; Walter, Klaudia; Memari, Yasin; Huang, Jie; Barnes, Michael R.; Beilby, John P.; Charoen, Pimphen; Danecek, Petr; Dudbridge, Frank; Forgetta, Vincenzo; Greenwood, Celia; Grundberg, Elin; Johnson, Andrew D.; Hui, Jennie; Lim, Ee M.; McCarthy, Shane; [...]Whole-genome sequence-based analysis of thyroid functionView onlineSchließen
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Published in: Nature Communications
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Timpson, Nicholas J.; Walter, Klaudia; Min, Josine L.; Tachmazidou, Ioanna; Malerba, Giovanni; Shin, So-Youn; Chen, Lu; Futema, Marta; Southam, Lorraine; Iotchkova, Valentina; Cocca, Massimiliano; Huang, Jie; Memari, Yasin; McCarthy, Shane; Danecek, Petr; Muddyman, Dawn; Mangino, Massimo; Menni, Cristina; Perry, John R. B.; Ring, Susan M.; Gaye, Amadou; Dedoussis, George; Farmaki, Aliki-Eleni; Burton, Paul; [...]A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in EuropeansView onlineSchließen
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Published in: Nature Communications
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Warrington, Nicole M.; Beaumont, Robin N.; Horikoshi, Momoko; Day, Felix R.; Helgeland, Øyvind; Laurin, Charles; Bacelis, Jonas; Peng, Shouneng; Hao, Ke; Feenstra, Bjarke; Wood, Andrew R.; Mahajan, Anubha; Tyrrell, Jessica; Robertson, Neil R.; Rayner, N. William; Qiao, Zhen; Moen, Gunn-Helen; Vaudel, Marc; Marsit, Carmen J.; Chen, Jia; Nodzenski, Michael; Schnurr, Theresia M.; Zafarmand, Mohammad H.; Bradfield, Jonathan P.; [...]Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factorsView onlineSchließen
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Published in: Nature Genetics
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Arce Vargas, Frederick; Furness, Andrew J.S.; Litchfield, Kevin; Joshi, Kroopa; Rosenthal, Rachel; Ghorani, Ehsan; Solomon, Isabelle; Lesko, Marta H.; Ruef, Nora; Roddie, Claire; Henry, Jake Y.; Spain, Lavinia; Ben Aissa, Assma; Georgiou, Andrew; Wong, Yien Ning Sophia; Smith, Myles; Strauss, Dirk; Hayes, Andrew; Nicol, David; O'Brien, Tim; Mårtensson, Linda; Ljungars, Anne; Teige, Ingrid; Frendéus, Björn; [...]Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 AntibodiesView onlineSchließen
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Published in: Cancer Cell
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Day, Felix R; Thompson, Deborah J; Helgason, Hannes; Chasman, Daniel I; Finucane, Hilary; Sulem, Patrick; Ruth, Katherine S; Whalen, Sean; Sarkar, Abhishek K; Albrecht, Eva; Altmaier, Elisabeth; Amini, Marzyeh; Barbieri, Caterina M; Boutin, Thibaud; Campbell, Archie; Demerath, Ellen; Giri, Ayush; He, Chunyan; Hottenga, Jouke J; Karlsson, Robert; Kolcic, Ivana; Loh, Po-Ru; Lunetta, Kathryn L; Mangino, Massimo; [...]Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer riskView onlineSchließen
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Published in: Nature Genetics
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Barban, Nicola; Jansen, Rick; de Vlaming, Ronald; Vaez, Ahmad; Mandemakers, Jornt J; Tropf, Felix C; Shen, Xia; Wilson, James F; Chasman, Daniel I; Nolte, Ilja M; Tragante, Vinicius; van der Laan, Sander W; Perry, John R B; Kong, Augustine; Ahluwalia, Tarunveer S; Albrecht, Eva; Yerges-Armstrong, Laura; Atzmon, Gil; Auro, Kirsi; Ayers, Kristin; Bakshi, Andrew; Ben-Avraham, Danny; Berger, Klaus; Bergman, Aviv; [...]Genome-wide analysis identifies 12 loci influencing human reproductive behaviorView onlineSchließen
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Published in: Nature Genetics
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Lu, Yingchang; Day, Felix R.; Gustafsson, Stefan; Buchkovich, Martin L.; Na, Jianbo; Bataille, Veronique; Cousminer, Diana L.; Dastani, Zari; Drong, Alexander W.; Esko, Tõnu; Evans, David M.; Falchi, Mario; Feitosa, Mary F.; Ferreira, Teresa; Hedman, Åsa K.; Haring, Robin; Hysi, Pirro G.; Iles, Mark M.; Justice, Anne E.; Kanoni, Stavroula; Lagou, Vasiliki; Li, Rui; Li, Xin; Locke, Adam; [...]New loci for body fat percentage reveal link between adiposity and cardiometabolic disease riskView onlineSchließen
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Published in: Nature Communications
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Okbay, Aysu; Wu, Yeda; Wang, Nancy; Jayashankar, Hariharan; Bennett, Michael; Nehzati, Seyed Moeen; Sidorenko, Julia; Kweon, Hyeokmoon; Goldman, Grant; Gjorgjieva, Tamara; Jiang, Yunxuan; Hicks, Barry; Tian, Chao; Hinds, David A.; Ahlskog, Rafael; Magnusson, Patrik K. E.; Oskarsson, Sven; Hayward, Caroline; Campbell, Archie; Porteous, David J.; Freese, Jeremy; Herd, Pamela; Agee, Michelle; Alipanahi, Babak; [...]Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individualsView onlineSchließen
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Published in: Nature Genetics
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Ligthart, Symen; Vaez, Ahmad; Võsa, Urmo; Stathopoulou, Maria G.; de Vries, Paul S.; Prins, Bram P.; Van der Most, Peter J.; Tanaka, Toshiko; Naderi, Elnaz; Rose, Lynda M.; Wu, Ying; Karlsson, Robert; Barbalic, Maja; Lin, Honghuang; Pool, René; Zhu, Gu; Macé, Aurélien; Sidore, Carlo; Trompet, Stella; Mangino, Massimo; Sabater-Lleal, Maria; Kemp, John P.; Abbasi, Ali; Kacprowski, Tim; [...]Genome Analyses of 200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex DisordersView onlineSchließen
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Published in: The American Journal of Human Genetics
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Marioni, Riccardo E.; Ritchie, Stuart J.; Joshi, Peter K.; Hagenaars, Saskia P.; Okbay, Aysu; Fischer, Krista; Adams, Mark J.; Hill, W. David; Davies, Gail; Nagy, Reka; Amador, Carmen; Läll, Kristi; Metspalu, Andres; Liewald, David C.; Campbell, Archie; Wilson, James F.; Hayward, Caroline; Esko, Tõnu; Porteous, David J.; Gale, Catharine R.; Deary, Ian J.; Okbay, Aysu; Beauchamp, Jonathan P.; Fontana, Mark A.; [...]Genetic variants linked to education predict longevityView onlineSchließen
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Published in: Proceedings of the National Academy of Sciences
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Walter, Klaudia; Min, Josine L.; Huang, Jie; Crooks, Lucy; Memari, Yasin; McCarthy, Shane; Perry, John R. B.; Xu, ChangJiang; Futema, Marta; Lawson, Daniel; Iotchkova, Valentina; Schiffels, Stephan; Hendricks, Audrey E.; Danecek, Petr; Li, Rui; Floyd, James; Wain, Louise V.; Barroso, Inês; Humphries, Steve E.; Hurles, Matthew E.; Zeggini, Eleftheria; Barrett, Jeffrey C.; Plagnol, Vincent; Brent Richards, J.; [...]The UK10K project identifies rare variants in health and diseaseView onlineSchließen
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Published in: Nature
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Graff, Mariaelisa; Scott, Robert A.; Justice, Anne E.; Young, Kristin L.; Feitosa, Mary F.; Barata, Llilda; Winkler, Thomas W.; Chu, Audrey Y.; Mahajan, Anubha; Hadley, David; Xue, Luting; Workalemahu, Tsegaselassie; Heard-Costa, Nancy L.; den Hoed, Marcel; Ahluwalia, Tarunveer S.; Qi, Qibin; Ngwa, Julius S.; Renström, Frida; Quaye, Lydia; Eicher, John D.; Hayes, James E.; Cornelis, Marilyn; Kutalik, Zoltan; Lim, Elise; [...]Correction: Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adultsView onlineSchließen
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Published in: PLOS Genetics
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Graff, Mariaelisa; Scott, Robert A.; Justice, Anne E.; Young, Kristin L.; Feitosa, Mary F.; Barata, Llilda; Winkler, Thomas W.; Chu, Audrey Y.; Mahajan, Anubha; Hadley, David; Xue, Luting; Workalemahu, Tsegaselassie; Heard-Costa, Nancy L.; den Hoed, Marcel; Ahluwalia, Tarunveer S.; Qi, Qibin; Ngwa, Julius S.; Renström, Frida; Quaye, Lydia; Eicher, John D.; Hayes, James E.; Cornelis, Marilyn; Kutalik, Zoltan; Lim, Elise; [...]Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adultsView onlineSchließen
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Published in: PLOS Genetics
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Okbay, Aysu; Beauchamp, Jonathan P.; Fontana, Mark Alan; Lee, James J.; Pers, Tune H.; Rietveld, Cornelius A.; Turley, Patrick; Chen, Guo-Bo; Emilsson, Valur; Meddens, S. Fleur W.; Oskarsson, Sven; Pickrell, Joseph K.; Thom, Kevin; Timshel, Pascal; de Vlaming, Ronald; Abdellaoui, Abdel; Ahluwalia, Tarunveer S.; Bacelis, Jonas; Baumbach, Clemens; Bjornsdottir, Gyda; Brandsma, Johannes H.; Pina Concas, Maria; Derringer, Jaime; Furlotte, Nicholas A.; [...]Genome-wide association study identifies 74 loci associated with educational attainmentView onlineSchließen
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Published in: Nature
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Ried, Janina S.; Jeff M., Janina; Chu, Audrey Y.; Bragg-Gresham, Jennifer L.; van Dongen, Jenny; Huffman, Jennifer E.; Ahluwalia, Tarunveer S.; Cadby, Gemma; Eklund, Niina; Eriksson, Joel; Esko, Tõnu; Feitosa, Mary F.; Goel, Anuj; Gorski, Mathias; Hayward, Caroline; Heard-Costa, Nancy L.; Jackson, Anne U.; Jokinen, Eero; Kanoni, Stavroula; Kristiansson, Kati; Kutalik, Zoltán; Lahti, Jari; Luan, Jian'an; Mägi, Reedik; [...]A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shapeView onlineSchließen
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Published in: Nature Communications
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Berndt, Sonja I; Gustafsson, Stefan; Mägi, Reedik; Ganna, Andrea; Wheeler, Eleanor; Feitosa, Mary F; Justice, Anne E; Monda, Keri L; Croteau-Chonka, Damien C; Day, Felix R; Esko, Tõnu; Fall, Tove; Ferreira, Teresa; Gentilini, Davide; Jackson, Anne U; Luan, Jian'an; Randall, Joshua C; Vedantam, Sailaja; Willer, Cristen J; Winkler, Thomas W; Wood, Andrew R; Workalemahu, Tsegaselassie; Hu, Yi-Juan; Lee, Sang Hong; [...]Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architectureView onlineSchließen
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Published in: Nature Genetics
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Hu, Yi-Juan; Berndt, Sonja I.; Gustafsson, Stefan; Ganna, Andrea; Hirschhorn, Joel; North, Kari E.; Ingelsson, Erik; Lin, Dan-Yu; Berndt, Sonja I.; Gustafsson, Stefan; Mägi, Reedik; Ganna, Andrea; Wheeler, Eleanor; Feitosa, Mary F.; Justice, Anne E.; Monda, Keri L.; Croteau-Chonka, Damien C.; Day, Felix R.; Esko, Tõnu; Fall, Tove; Ferreira, Teresa; Gentilini, Davide; Jackson, Anne U.; Luan, Jian’an; [...]Meta-analysis of Gene-Level Associations for Rare Variants Based on Single-Variant StatisticsView onlineSchließen
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Published in: The American Journal of Human Genetics
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Winkler, Thomas W.; Justice, Anne E.; Graff, Mariaelisa; Barata, Llilda; Feitosa, Mary F.; Chu, Su; Czajkowski, Jacek; Esko, Tõnu; Fall, Tove; Kilpeläinen, Tuomas O.; Lu, Yingchang; Mägi, Reedik; Mihailov, Evelin; Pers, Tune H.; Rüeger, Sina; Teumer, Alexander; Ehret, Georg B.; Ferreira, Teresa; Heard-Costa, Nancy L.; Karjalainen, Juha; Lagou, Vasiliki; Mahajan, Anubha; Neinast, Michael D.; Prokopenko, Inga; [...]Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction StudyView onlineSchließen
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Published in: PLOS Genetics
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Winkler, Thomas W.; Justice, Anne E.; Graff, Mariaelisa; Barata, Llilda; Feitosa, Mary F.; Chu, Su; Czajkowski, Jacek; Esko, Tõnu; Fall, Tove; Kilpeläinen, Tuomas O.; Lu, Yingchang; Mägi, Reedik; Mihailov, Evelin; Pers, Tune H.; Rüeger, Sina; Teumer, Alexander; Ehret, Georg B.; Ferreira, Teresa; Heard-Costa, Nancy L.; Karjalainen, Juha; Lagou, Vasiliki; Mahajan, Anubha; Neinast, Michael D.; Prokopenko, Inga; [...]The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction StudyView onlineSchließen
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Published in: PLOS Genetics
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Gorman, Kathleen M.; Meyer, Esther; Grozeva, Detelina; Spinelli, Egidio; McTague, Amy; Sanchis-Juan, Alba; Carss, Keren J.; Bryant, Emily; Reich, Adi; Schneider, Amy L.; Pressler, Ronit M.; Simpson, Michael A.; Debelle, Geoff D.; Wassmer, Evangeline; Morton, Jenny; Sieciechowicz, Diana; Jan-Kamsteeg, Eric; Paciorkowski, Alex R.; King, Mary D.; Cross, J. Helen; Poduri, Annapurna; Mefford, Heather C.; Scheffer, Ingrid E.; Haack, Tobias B.; [...]Bi-allelic Loss-of-Function CACNA1B Mutations in Progressive Epilepsy-DyskinesiaView onlineSchließen
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Published in: The American Journal of Human Genetics