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Ho, Aileen K.; Horton, Mike C.; Landwehrmeyer, G. Bernhard; Burgunder, Jean-Marc; Tennant, Alan; Downie, Lorna; Jack, Roisin; Matheson, Kirsty; Miedzybrodzka, Zosia; Rae, Daniela; Simpson, Sheila A.; Summers, Fiona; Ure, Alexandra; Vaughan, Vivien; Akhtar, Shahbana; Crooks, Jenny; Curtis, Adrienne; de Souza (Keylock), Jenny; Piedad, John; Rickards, Hugh; Wright, Jan; Coulthard, Elizabeth; Gethin, Louise; Hayward, Beverley; [...]Meaningful and Measurable Health Domains in Huntington’s Disease: Large-Scale Validation of the Huntington’s Disease Health-Related Quality of Life Questionnaire Across Severity StagesView onlineSchließen
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Published in: Value in Health
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Afentou, Nafsika; Frew, Emma; Mehta, Samir; Ives, Natalie J.; Woolley, Rebecca L.; Brettell, Elizabeth A.; Khan, Adam R.; Milford, David V.; Bockenhauer, Detlef; Saleem, Moin A.; Hall, Angela S.; Koziell, Ania; Maxwell, Heather; Hegde, Shivaram; Finlay, Eric; Gilbert, Rodney D.; Jones, Caroline; McKeever, Karl; Cook, Wendy; Webb, Nicholas J. A.; Christian, Martin T.; Webb, Nicholas; Christian, Martin; Ives, Natalie; [...]Economic Evaluation of Using Daily Prednisolone versus Placebo at the Time of an Upper Respiratory Tract Infection for the Management of Children with Steroid-Sensitive Nephrotic Syndrome: A Model-Based AnalysisView onlineSchließen
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Published in: PharmacoEconomics - Open
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Áñez, Germán; Dunkle, Lisa M.; Gay, Cynthia L.; Kotloff, Karen L.; Adelglass, Jeffrey M.; Essink, Brandon; Campbell, James D.; Cloney-Clark, Shane; Zhu, Mingzhu; Plested, Joyce S.; Roychoudhury, Pavitra; Greninger, Alexander L.; Patel, Nita; McGarry, Alice; Woo, Wayne; Cho, Iksung; Glenn, Gregory M.; Dubovsky, Filip; Andersen, James; Fearon, Szheckera; Negron, Rosa; Medina, Amy; Figueroa, Colleen; Smith, Courtney; [...]Safety, Immunogenicity, and Efficacy of the NVX-CoV2373 COVID-19 Vaccine in Adolescents : A Randomized Clinical Trial : A Randomized Clinical TrialView onlineSchließen
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Published in: JAMA Network Open
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Teslovich, Tanya M.; Musunuru, Kiran; Smith, Albert V.; Edmondson, Andrew C.; Stylianou, Ioannis M.; Koseki, Masahiro; Pirruccello, James P.; Ripatti, Samuli; Chasman, Daniel I.; Willer, Cristen J.; Johansen, Christopher T.; Fouchier, Sigrid W.; Isaacs, Aaron; Peloso, Gina M.; Barbalic, Maja; Ricketts, Sally L.; Bis, Joshua C.; Aulchenko, Yurii S.; Thorleifsson, Gudmar; Feitosa, Mary F.; Chambers, John; Orho-Melander, Marju; Melander, Olle; Johnson, Toby; [...]Biological, clinical and population relevance of 95 loci for blood lipidsView onlineSchließen
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Published in: Nature
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Johnstone, Jennie; Meade, Maureen; Lauzier, François; Marshall, John; Duan, Erick; Dionne, Joanna; Arabi, Yaseen M.; Heels-Ansdell, Diane; Thabane, Lehana; Lamarche, Daphnee; Surette, Michael; Zytaruk, Nicole; Mehta, Sangeeta; Dodek, Peter; McIntyre, Lauralyn; English, Shane; Rochwerg, Bram; Karachi, Tim; Henderson, William; Wood, Gordon; Ovakim, Daniel; Herridge, Margaret; Granton, John; Wilcox, M. Elizabeth; [...]Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients : A Randomized Clinical Trial : A Randomized Clinical TrialView onlineSchließen
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Published in: JAMA
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Niggl, Eva; Bouman, Arjan; Briere, Lauren C.; Hoogenboezem, Remco M.; Wallaard, Ilse; Park, Joohyun; Admard, Jakob; Wilke, Martina; Harris-Mostert, Emilio D.R.O.; Elgersma, Minetta; Bain, Jennifer; Balasubramanian, Meena; Banka, Siddharth; Benke, Paul J.; Bertrand, Miriam; Blesson, Alyssa E.; Clayton-Smith, Jill; Ellingford, Jamie M.; Gillentine, Madelyn A.; Goodloe, Dana H.; Haack, Tobias B.; Jain, Mahim; Krantz, Ian; Luu, Sharon M.; [...]HNRNPC haploinsufficiency affects alternative splicing of intellectual disability-associated genes and causes a neurodevelopmental disorderView onlineSchließen
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Published in: The American Journal of Human Genetics
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Kymes, Steven M.; Oden, Neal L.; VanVeldhuisen, Paul C.; Scott, Ingrid U.; Ip, Michael S.; Blodi, Barbara A.; King, Jacquie; Williams, George A; Abraham, Prema; Bement-Stump, Beth; Callahan, Leah; Dockter, Mindi; Livermont, Kristi; Nixon, Robert; Parks, Dan; Steinle, Nathan; Thompson, Alison; Yu, Dylan; Bailey, Steven; Barth, Jordan; Blefgen, Sara; Campbell, J. Peter; Flaxel, Christina; Fujisaki, Brad; [...]Cost-Utility Comparison of Bevacizumab and Aflibercept in the Treatment of Central or Hemiretinal Vein Occlusion in the SCORE2 TrialView onlineSchließen
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Published in: JAMA Ophthalmology
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Scott, Ingrid U.; Oden, Neal L.; VanVeldhuisen, Paul C.; Ip, Michael S.; Blodi, Barbara A.; Williams, George A; Abraham, Prema; Bement-Stump, Beth; Callahan, Leah; Dockter, Mindi; Livermont, Kristi; Nixon, Robert; Parks, Dan; Steinle, Nathan; Thompson, Alison; Yu, Dylan; Bailey, Steven; Barth, Jordan; Blefgen, Sara; Campbell, J. Peter; Flaxel, Christina; Fujisaki, Brad; Howell, Christopher; Hui, Jocelyn; [...]Baseline Characteristics and Outcomes After Anti–Vascular Endothelial Growth Factor Therapy for Macular Edema in Participants With Hemiretinal Vein Occlusion Compared With Participants With Central Retinal Vein Occlusion : Study of Comparative Treatments for Retinal Vein Occlusion 2 (SCORE2) Report 18 : Study of Comparative Treatments for Retinal Vein Occlusion 2 (SCORE2) Report 18View onlineSchließen
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Published in: JAMA Ophthalmology
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Aref, Ahmad A.; Scott, Ingrid U.; VanVeldhuisen, Paul C.; King, Jacquie; Ip, Michael S.; Blodi, Barbara A.; Oden, Neal L.; Williams, George A; Abraham, Prema; Bement-Stump, Beth; Callahan, Leah; Dockter, Mindi; Livermont, Kristi; Nixon, Robert; Parks, Dan; Steinle, Nathan; Thompson, Alison; Yu, Dylan; Bailey, Steven; Barth, Jordan; Blefgen, Sara; Campbell, J. Peter; Flaxel, Christina; Fujisaki, Brad; [...]Intraocular Pressure–Related Events After Anti–Vascular Endothelial Growth Factor Therapy for Macular Edema Due to Central Retinal Vein Occlusion or Hemiretinal Vein Occlusion : SCORE2 Report 16 on a Secondary Analysis of a Randomized Clinical Trial : SCORE2 Report 16 on a Secondary Analysis of a Randomized Clinical TrialView onlineSchließen
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Published in: JAMA Ophthalmology
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Zhou, Xueya; Feliciano, Pamela; Shu, Chang; Wang, Tianyun; Astrovskaya, Irina; Hall, Jacob B.; Obiajulu, Joseph U.; Wright, Jessica R.; Murali, Shwetha C.; Xu, Simon Xuming; Brueggeman, Leo; Thomas, Taylor R.; Marchenko, Olena; Fleisch, Christopher; Barns, Sarah D.; Snyder, LeeAnne Green; Han, Bing; Chang, Timothy S.; Turner, Tychele N.; Harvey, William T.; Nishida, Andrew; O’Roak, Brian J.; Geschwind, Daniel H.; Adams, Adrienne; [...]Integrating de novo and inherited variants in 42,607 autism cases identifies mutations in new moderate-risk genesView onlineSchließen
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Published in: Nature Genetics
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Schmidt, Andrew L.; Tucker, Matthew D.; Bakouny, Ziad; Labaki, Chris; Hsu, Chih-Yuan; Shyr, Yu; Armstrong, Andrew J.; Beer, Tomasz M.; Bijjula, Ragneel R.; Bilen, Mehmet A.; Connell, Cindy F.; Dawsey, Scott Joseph; Faller, Bryan; Gao, Xin; Gartrell, Benjamin A.; Gill, David; Gulati, Shuchi; Halabi, Susan; Hwang, Clara; Joshi, Monika; Khaki, Ali Raza; Menon, Harry; Morris, Michael J.; Puc, Matthew; [...]Association Between Androgen Deprivation Therapy and Mortality Among Patients With Prostate Cancer and COVID-19View onlineSchließen
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Published in: JAMA Network Open
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Lango Allen, Hana; Estrada, Karol; Lettre, Guillaume; Berndt, Sonja I.; Weedon, Michael N.; Rivadeneira, Fernando; Willer, Cristen J.; Jackson, Anne U.; Vedantam, Sailaja; Raychaudhuri, Soumya; Ferreira, Teresa; Wood, Andrew R.; Weyant, Robert J.; Segrè, Ayellet V.; Speliotes, Elizabeth K.; Wheeler, Eleanor; Soranzo, Nicole; Park, Ju-Hyun; Yang, Jian; Gudbjartsson, Daniel; Heard-Costa, Nancy L.; Randall, Joshua C.; Qi, Lu; Vernon Smith, Albert; [...]Hundreds of variants clustered in genomic loci and biological pathways affect human heightView onlineSchließen
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Published in: Nature
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Maguire, Maureen G.; Liu, Danni; Bressler, Susan B.; Friedman, Scott M.; Melia, Michele; Stockdale, Cynthia R.; Glassman, Adam R.; Sun, Jennifer K.; Browning, David; Antoszyk, Andrew N.; Price, Angela K.; Murphy, Brittany A; Fleming, Christina J.; Herby, Jenna T.; Walker, Merri F; McClain, Ashley A.; Jones, Taylor S.; Fredenberg, Sherry L.; Ennis, Sarah A.; Grupp, Autumn C.; Gentile, Angella K.; Gallagher, Kelly R; Breglio, Erica; Lester, Gina M.; [...]Lapses in Care Among Patients Assigned to Ranibizumab for Proliferative Diabetic Retinopathy : A Post Hoc Analysis of a Randomized Clinical Trial : A Post Hoc Analysis of a Randomized Clinical TrialView onlineSchließen
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Published in: JAMA Ophthalmology
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Aggarwal, Dinesh; Warne, Ben; Jahun, Aminu S.; Hamilton, William L.; Fieldman, Thomas; du Plessis, Louis; Hill, Verity; Blane, Beth; Watkins, Emmeline; Wright, Elizabeth; Hall, Grant; Ludden, Catherine; Myers, Richard; Hosmillo, Myra; Chaudhry, Yasmin; Pinckert, Malte L.; Georgana, Iliana; Izuagbe, Rhys; Leek, Danielle; Nsonwu, Olisaeloka; Hughes, Gareth J.; Packer, Simon; Page, Andrew J.; Metaxaki, Marina; [...]Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmissionView onlineSchließen
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Published in: Nature Communications
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Abdelhady, Hesham; Abdelrazik, Marwa; Abdi, Zakee; Abdo, David; Abdulle, Amina; Abel, Lynn; Abouzeenni, Shrefee; Abrahamson, Gail; Abusamra, Yousuf; Adams, Lisa; Adebambo, Olumide; Ademokun, Debo; Adhikari, Neill; Affron, Dominic; Aggarwal, Anu; Agno, Ronan; Ahmad, Humayun; Ahmad, Norfaizan; Ahmed, Sophia; Ainscough, Kate; Ainsworth, James; Airoldi, Giulia; Aitken, Lindianne; Ajeneye, Francis; [...]Effect of Convalescent Plasma on Organ Support–Free Days in Critically Ill Patients With COVID-19 : A Randomized Clinical Trial : A Randomized Clinical TrialView onlineSchließen
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Published in: JAMA
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Joung, Rachel Hae-Soo; Mullett, Timothy W.; Kurtzman, Scott H.; Shafir, Sarah; Harris, James B.; Yao, Katharine A.; Bilimoria, Karl Y.; Cance, William G.; Nelson, Heidi; Abedi, Ali; Acharya, Sheetal; Adams, Karen T.; Agarwal, Rishi; Agarwal, Sachin; Ahmad, Rima; Albaneze, Philip; Aldis, Kimberly; Allen, Ahkeel; Allman, Shayla; Alsen, Meiling; Ansteth, Mindy; Appiah, Angela A.; Arentz, Candy; Arias, Amanda (Lori); [...]Evaluation of a National Quality Improvement Collaborative for Improving Cancer ScreeningView onlineSchließen
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Published in: JAMA Network Open
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Pairo-Castineira, Erola; Rawlik, Konrad; Bretherick, Andrew D.; Qi, Ting; Wu, Yang; Nassiri, Isar; McConkey, Glenn A.; Zechner, Marie; Klaric, Lucija; Griffiths, Fiona; Oosthuyzen, Wilna; Kousathanas, Athanasios; Richmond, Anne; Millar, Jonathan; Russell, Clark D.; Malinauskas, Tomas; Thwaites, Ryan; Morrice, Kirstie; Keating, Sean; Maslove, David; Nichol, Alistair; Semple, Malcolm G.; Knight, Julian; Shankar-Hari, Manu; [...]Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19View onlineSchließen
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Published in: Nature
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Pairo-Castineira, Erola; Rawlik, Konrad; Bretherick, Andrew D.; Qi, Ting; Wu, Yang; Nassiri, Isar; McConkey, Glenn A.; Zechner, Marie; Klaric, Lucija; Griffiths, Fiona; Oosthuyzen, Wilna; Kousathanas, Athanasios; Richmond, Anne; Millar, Jonathan; Russell, Clark D.; Malinauskas, Tomas; Thwaites, Ryan; Morrice, Kirstie; Keating, Sean; Maslove, David; Nichol, Alistair; Semple, Malcolm G.; Knight, Julian; Shankar-Hari, Manu; [...]GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19View onlineSchließen
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Published in: Nature
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Kousathanas, Athanasios; Pairo-Castineira, Erola; Rawlik, Konrad; Stuckey, Alex; Odhams, Christopher A.; Walker, Susan; Russell, Clark D.; Malinauskas, Tomas; Wu, Yang; Millar, Jonathan; Shen, Xia; Elliott, Katherine S.; Griffiths, Fiona; Oosthuyzen, Wilna; Morrice, Kirstie; Keating, Sean; Wang, Bo; Rhodes, Daniel; Klaric, Lucija; Zechner, Marie; Parkinson, Nick; Siddiq, Afshan; Goddard, Peter; Donovan, Sally; [...]Whole-genome sequencing reveals host factors underlying critical COVID-19View onlineSchließen
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Published in: Nature
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de Silva, Thushan I.; Liu, Guihai; Lindsey, Benjamin B.; Dong, Danning; Moore, Shona C.; Hsu, Nienyun Sharon; Shah, Dhruv; Wellington, Dannielle; Mentzer, Alexander J.; Angyal, Adrienn; Brown, Rebecca; Parker, Matthew D.; Ying, Zixi; Yao, Xuan; Turtle, Lance; Dunachie, Susanna; Maini, Mala K.; Ogg, Graham; Knight, Julian C.; Peng, Yanchun; Rowland-Jones, Sarah L.; Dong, Tao; Aanensen, David M.; Abudahab, Khalil; [...]The impact of viral mutations on recognition by SARS-CoV-2 specific T cellsView onlineSchließen
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Published in: iScience