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Prenißl, Niklas [Author] ; Garbers, Christoph [Degree supervisor] Christian-Albrechts-Universität zu Kiel

Die Metalloprotease ADAM17 : Entwicklung potenzieller Makrophagen-spezifischer Inhibitoren und Beeinflussung durch Inhibitoren des Interleukin-6 Rezeptors

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Kiel: Universitätsbibliothek Kiel, 2021
Koch, Lydia Friederike [Author] ; Garbers, Christoph [Degree supervisor]; Janssen, Ottmar Johannes [Degree supervisor] Christian-Albrechts-Universität zu Kiel

Proteolyse des Interleukin-11-Rezeptors durch die Protease RHBDL2

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Kiel: Universitätsbibliothek Kiel, 2021
Lokau, Juliane [Author]; Garbers, Christoph [Author]

Interleukin-6-interleukin-11 receptor chimeras reveal ionomycin-induced proteolysis beyond ADAM10

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2021

Published in: Vereinigung der Europäischen Biochemischen Gesellschaften: FEBS letters ; 595(2021), 24, Seite 3072-3082
Garbers, Christoph Andreas [Author] ; Schleper, Peter [Degree supervisor]

A Precision Top Quark Mass Measurement with a Profile Likelihood Nuisance Fit

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Hamburg: Staats- und Universitätsbibliothek Hamburg Carl von Ossietzky, 2022
Heise, Denise [Author] ; Scheller, Jürgen [Degree supervisor]; Krüger, Martina [Other]; Garbers, Christoph [Other]

Herstellung und Charakterisierung von inhibitorischen Fusionsproteinen zur Modulation der Interleukin 6 Signaltransduktion

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Düsseldorf: Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2022
Garbers, Christoph [Author]; Rose-John, Stefan [Author]

Soluble interleukin-6 receptor in patients with JAK2V617F somatic mutation and myeloproliferative neoplasm

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2020

Published in: EClinicalMedicine ; Bd. 22.2020, Art.-Nr. 100340, insgesamt 1 Seite
Kespohl, Birte [Author]; Hartig, Roland [Author]; Garbers, Yvonne [Author]; Lokau, Juliane [Author]; Garbers, Christoph [Author]

Coding variants of the interleukin-11 receptor with reduced protein maturation show protease-dependent trans-signaling and transduce normal STAT3 signaling

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2023

Published in: Genes & diseases ; 10(2023), 2, Seite 373-376
Lokau, Juliane [Author]; Garbers, Yvonne [Author]; Grötzinger, Joachim [Author]; Garbers, Christoph [Author]

A single aromatic residue in sgp130Fc/olamkicept allows the discrimination between interleukin-6 and interleukin-11 trans-signaling

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2021

Published in: iScience ; 24(2021), 11, Artikel-ID 103309
Runge, Josephine [Author]; Garbers, Christoph [Author]; Lokau, Juliane [Author]

The role of interleukin-6 classic and trans-signaling and interleukin-11 classic signaling in gastric cancer cells

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2024

Published in: Contemporary oncology ; 28(2024), 2, Seite 105-113
Lokau, Juliane [Author]; Petasch, Lynn M. [Author]; Garbers, Christoph [Author]

The soluble IL-2 receptor α/CD25 as a modulator of IL-2 function

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2024

Published in: Immunology ; 171(2024), 3, Seite 377-387
Lokau, Juliane [Author]; Schoeder, Victor [Author]; Haybäck, Johannes [Author]; Garbers, Christoph [Author]

Jak-Stat signaling induced by interleukin-6 family cytokines in hepatocellular carcinoma

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2019

Published in: Cancers ; Bd. 11.2019, 11, Art.-Nr. 1704, insges. 17 S.
Lokau, Juliane [Author]; Kleinegger, Florian [Author]; Garbers, Yvonne [Author]; Wätzig, Georg H. [Author]; Grötzinger, Joachim [Author]; Rose-John, Stefan [Author]; Haybäck, Johannes [Author]; Garbers, Christoph [Author]

Tocilizumab does not block interleukin-6 (IL-6) signaling in murine cells

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2020

Published in: PLOS ONE ; Bd. 15.2020, 5, Art.-Nr. e0232612, insges. 10 S.
Flynn, Charlotte M. [Author]; Kespohl, Birte [Author]; Daunke, Tina [Author]; Garbers, Yvonne [Author]; Düsterhöft, Stefan [Author]; Rose-John, Stefan [Author]; Haybäck, Johannes [Author]; Lokau, Juliane [Author]; Aparicio Siegmund, Samadhi [Author]; Garbers, Christoph [Author]

Interleukin-6 controls recycling and degradation, but not internalization of its receptors

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2021

Published in: The journal of biological chemistry ; 296(2021), Artikel-ID 100434
Flynn, Charlotte M. [Author]; Garbers, Yvonne [Author]; Lokau, Juliane [Author]; Wesch, Daniela [Author]; Schulte, Dominik Maria [Author]; Laudes, Matthias [Author]; Lieb, Wolfgang [Author]; Aparicio Siegmund, Samadhi [Author]; Garbers, Christoph [Author]

Activation of Toll-like receptor 2 (TLR2) induces Interleukin-6 trans-signaling

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2019

Published in: Scientific reports ; Bd. 9.2019, Art.-Nr. 7306, insges. 11 S.
Baldauf, Conny [Author]; Müller, Peter [Author]; Haage, Tobias Ronny [Author]; Adam-Frey, Stephanie [Author]; Lokau, Juliane [Author]; Garbers, Christoph [Author]; Fischer, Thomas [Author]

Anti-IL-6 cytokine treatment has no impact on elevated hematocrit and splenomegaly in a polycythemia vera mouse model

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2022

Published in: Blood advances ; 6(2022), 2, Seite 399-404
Koch, Lydia [Author]; Kespohl, Birte [Author]; Agthe, Maria [Author]; Schumertl, Tim [Author]; Düsterhöft, Stefan [Author]; Lemberg, Marius [Author]; Lokau, Juliane [Author]; Garbers, Christoph [Author]

Interleukin-11 (IL-11) receptor cleavage by the rhomboid protease RHBDL2 induces IL-11 trans-signaling

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10 February 2021

Published in: Federation of American Societies for Experimental Biology: The FASEB journal ; 35(2021), 3, Artikel-ID e21380, Seite 1-15
Koch, Lydia [Author]; Kespohl, Birte [Author]; Agthe, Maria [Author]; Schumertl, Tim [Author]; Düsterhöft, Stefan [Author]; Lemberg, Marius [Author]; Lokau, Juliane [Author]; Garbers, Christoph [Author]

Interleukin-11 (IL-11) receptor cleavage by the rhomboid protease RHBDL2 induces IL-11 trans-signaling

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Hoboken, NJ: Wiley, 04 January 2021

Published in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology ; 35 (2021) 3
Georgieva, Elizabeta [Author]; Leber, Stefan L. [Author]; Wex, Cora Barbara Anette [Author]; Garbers, Christoph [Author]

Perturbation of the actin cytoskeleton in human hepatoma cells influences interleukin-6 (IL-6) signaling, but not soluble IL-6 receptor generation or NF-[kappa]B activation

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2021

Published in: International journal of molecular sciences ; 22(2021), 13, Artikel-ID 7171
Guilherme, Malena dos Santos [Author]; Stoye, Nicolai M. [Author]; Rose-John, Stefan [Author]; Garbers, Christoph [Author]; Fellgiebel, Andreas [Author]; Endres, Kristina [Author]

The synthetic retinoid acitretin increases IL-6 in the central nervous system of Alzheimer disease model mice and human patients

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2019

Published in: Frontiers in aging neuroscience ; Bd. 11.2019, Art.-Nr. 182, insges. 7 S.
Prenissl, Niklas [Author]; Lokau, Juliane [Author]; Rose-John, Stefan [Author]; Haybäck, Johannes [Author]; Garbers, Christoph [Author]

Therapeutic blockade of the interleukin-6 receptor (IL-6R) allows sIL-6R generation by proteolytic cleavage

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2019

Published in: Cytokine ; 114(2019), Seite 1-5

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