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Ghazy, Ehab Mohamed Elbassiony [Author] ; Sippl, Wolfgang [Other]; Schutkowski, Mike [Other]; Rotili, Dante [Other]

Synthesis and biological characterization of novel inhibitors of histone deacetylases as anticancer and antiparasitic agents [Kumulative Dissertation]

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Halle (Saale): Universitäts- und Landesbibliothek Sachsen-Anhalt, 2022
Ghazy, Ehab Mohamed Elbassiony [Author] ; Sippl, Wolfgang [Degree supervisor]; Schutkowski, Mike [Degree supervisor]; Rotili, Dante [Degree supervisor] Martin-Luther-Universität Halle-Wittenberg

Synthesis and biological characterization of novel inhibitors of histone deacetylases as anticancer and antiparasitic agents [Kumulative Dissertation]

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Halle; Wittenberg, [2022?]
Coutinho Carneiro, Vitor [Author]; Abreu da Silva, Isabel Caetano de [Author]; Amaral, Murilo Sena [Author]; Pereira, Adriana S. A. [Author]; Silveira, Gilbert Oliveira [Author]; Pires, David da Silva [Author]; Verjovski-Almeida, Sergio [Author]; Dekker, Frank J. [Author]; Rotili, Dante [Author]; Mai, Antonello [Author]; Lopes-Torres, Eduardo José [Author]; Robaa, Dina [Author]; Sippl, Wolfgang [Author]; Pierce, Raymond J. [Author]; Borrello, M. Teresa [Author]; Ganesan, A. [Author]; Lancelot, Julien [Author]; Thiengo, Silvana [Author]; Fernandez, Monica Ammon [Author]; Vicentino, Amanda Roberta Revoredo [Author]; Mourão, Marina Moraes [Author]; Coelho, Fernanda Sales [Author]; Fantappié, Marcelo Rosado [Author]

Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in Schistosoma mansoni

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2020

Published in: Public Library of Science: PLoS neglected tropical diseases ; 14 (2020,7), Artikel e0008332, 29 Seiten
Rotili, Dante; Mattevi, Andrea

At Long Last Potent and Selective KDM5 Inhibitors

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Elsevier BV, 2016

Published in: Cell Chemical Biology, 23 (2016) 7, Seite 749-751
Fiorentino, Francesco; Mai, Antonello; Rotili, Dante

Emerging Therapeutic Potential of SIRT6 Modulators

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American Chemical Society (ACS), 2021

Published in: Journal of Medicinal Chemistry, 64 (2021) 14, Seite 9732-9758
Fiorentino, Francesco; Mai, Antonello; Rotili, Dante

Lysine Acetyltransferase Inhibitors From Natural Sources

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Frontiers Media SA, 2020

Published in: Frontiers in Pharmacology, 11 (2020)
Fiorentino, Francesco; Menna, Martina; Rotili, Dante; Valente, Sergio; Mai, Antonello

METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey

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American Chemical Society (ACS), 2023

Published in: Journal of Medicinal Chemistry, 66 (2023) 3, Seite 1654-1677
Fiorentino, Francesco; Castiello, Carola; Mai, Antonello; Rotili, Dante

Therapeutic Potential and Activity Modulation of the Protein Lysine Deacylase Sirtuin 5

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American Chemical Society (ACS), 2022

Published in: Journal of Medicinal Chemistry, 65 (2022) 14, Seite 9580-9606
Tomaselli, Daniela; Lucidi, Alessia; Rotili, Dante; Mai, Antonello

Epigenetic polypharmacology: A new frontier for epi‐drug discovery

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Wiley, 2020

Published in: Medicinal Research Reviews, 40 (2020) 1, Seite 190-244
Tomaselli, Daniela; Steegborn, Clemens; Mai, Antonello; Rotili, Dante

Sirt4: A Multifaceted Enzyme at the Crossroads of Mitochondrial Metabolism and Cancer

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Frontiers Media SA, 2020

Published in: Frontiers in Oncology, 10 (2020)
Rotili, Dante; Mai, Antonello; Ambrogio, Ilaria; Fabrizi, Giancarlo

One‐Pot, High‐Yielding Synthesis of Novel Dihydrothiazolo[3,2‐a]pyrimidinones

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Informa UK Limited, 2006

Published in: Synthetic Communications, 36 (2006) 4, Seite 495-500
Rotili, Dante; Mai, Antonello; Ambrogio, Ilaria; Fabrizi, Giancarlo

One‐Pot, High‐Yielding Synthesis of Novel Dihydrothiazolo[3,2‐a]pyrimidinones

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Wiley, 2006

Published in: ChemInform, 37 (2006) 34
Ornaghi, Prisca; Rotili, Dante; Sbardella, Gianluca; Mai, Antonello; Filetici, Patrizia

A novel Gcn5p inhibitor represses cell growth, gene transcription and histone acetylation in budding yeast

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Elsevier BV, 2005

Published in: Biochemical Pharmacology, 70 (2005) 6, Seite 911-917
Wang, Jinping; Luo, Jinque; Rotili, Dante; Mai, Antonello; Steegborn, Clemens; Xu, Suowen; Jin, Zheng Gen

SIRT6 Protects Against Lipopolysaccharide-Induced Inflammation in Human Pulmonary Lung Microvascular Endothelial Cells

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Springer Science and Business Media LLC, 2024

Published in: Inflammation, 47 (2024) 1, Seite 323-332
Iuzzolino, Angela; Pellegrini, Francesca Romana; Rotili, Dante; Degrassi, Francesca; Trisciuoglio, Daniela

The α-tubulin acetyltransferase ATAT1: structure, cellular functions, and its emerging role in human diseases

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Springer Science and Business Media LLC, 2024

Published in: Cellular and Molecular Life Sciences, 81 (2024) 1
Fiorentino, Francesco; Nocentini, Alessio; Rotili, Dante; Supuran, Claudiu T.; Mai, Antonello

Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII

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Informa UK Limited, 2023

Published in: Journal of Enzyme Inhibition and Medicinal Chemistry, 38 (2023) 1
Fabbrizi, Emanuele; Fiorentino, Francesco; Carafa, Vincenzo; Altucci, Lucia; Mai, Antonello; Rotili, Dante

Emerging Roles of SIRT5 in Metabolism, Cancer, and SARS-CoV-2 Infection

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MDPI AG, 2023

Published in: Cells, 12 (2023) 6, Seite 852
Negri, Aide; Marozzi, Marina; Trisciuoglio, Daniela; Rotili, Dante; Mai, Antonello; Rizzi, Federica

Simultaneous administration of EZH2 and BET inhibitors inhibits proliferation and clonogenic ability of metastatic prostate cancer cells

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Informa UK Limited, 2023

Published in: Journal of Enzyme Inhibition and Medicinal Chemistry, 38 (2023) 1
Fiorentino, Francesco; Rotili, Dante; Mai, Antonello; Bolla, Jani R.; Robinson, Carol V.

Mass spectrometry enables the discovery of inhibitors of an LPS transport assembly via disruption of protein–protein interactions

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Royal Society of Chemistry (RSC), 2021

Published in: Chemical Communications, 57 (2021) 82, Seite 10747-10750
Fiorentino, Francesco; Carafa, Vincenzo; Favale, Gregorio; Altucci, Lucia; Mai, Antonello; Rotili, Dante

The Two-Faced Role of SIRT6 in Cancer

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MDPI AG, 2021

Published in: Cancers, 13 (2021) 5, Seite 1156

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