University thesis:
Dissertation, Georg-August-Universität Göttingen, 2018
Footnote:
Description:
The CD14-Receptor plays a pivotal role in the recognition of pathogenic germs by the innate immune system. After the recognition of pathogenic germs the CD14-Receptor activates an immune response resulting in a release of proinflammatory cytokines. Therefore we suggested to prove the influence caused by genetic polymorphisms of CD14 on the immune response. By the results of other studies there was a heavy evidence for influencing the innate immune system by the CD14 SNP rs2569190. While the C-allele seems to increase the risk of developing an infection, the T-allele is associated with an im...