University thesis:
Dissertation, Georg-August-Universität Göttingen, 2017
Footnote:
Description:
The iBeetle screen project: Christiane Nüsslein-Volhard and Eric Wieschaus performed the first saturated forward genetic screen using random mutagenesis to identify genes important for embryonic development in Drosophila melanogaster. However, the Drosophila larval head turns outside in during embryogenesis as a result this involuted head lacks phenotypic markers for identification of defects. Moreover, perturbation of Drosophila head development often interferes with head involution making it difficult to identify the primary phenotype. Therefore, we decided to study head development in an...