• Media type: E-Article
  • Title: miR-125b affects mitochondrial biogenesis and impairs brite adipocyte formation and function
  • Contributor: Giroud, Maude [VerfasserIn]; Herzig, Stephan [VerfasserIn]; Scheideler, Marcel [VerfasserIn]
  • imprint: 15 June 2016
  • Published in: Molecular metabolism ; 5(2016), 8, Seite 615-625
  • Language: English
  • DOI: 10.1016/j.molmet.2016.06.005
  • ISSN: 2212-8778
  • Identifier:
  • Origination:
  • Footnote:
  • Description: miR-125b-5p levels negatively correlate with UCP1 expression in rodent and human. miR125b levels in white adipose tissue are positively correlated with BMI. miR-125b-5p modulates oxygen consumption. Mitochondriogenesis is controlled by miR-125b-5p. In vivo modulation of miR-125b-5p controls brown and brite adipocyte formation.
  • Access State: Open Access