Aging Hair

Media type: E-Book

Title: Aging Hair

Contains: 157326_1_En_1_BookFrontmatter_OnlinePDF.pdf; 157326_1_En_1_Chapter_OnlinePDF.pdf; 1; Gerontobiology of the Hair Follicle; Core Message; 1.1 Introduction; 1.2 Biologic vs. Chronologic Aging; 1.3 Variation in Hair Types During the Life of a Hair Follicle; 1.3.1 Lanugo-to-Vellus Hair Follicle Transformation; 1.3.1.1 Congenital Universal Hypertrichosis; 1.3.2 Vellus-to-Terminal Hair Follicle Transformation; 1.3.3 Terminal-to-Vellus Hair Follicle Transformation; 1.4 Age-Related Hair Growth Variation; 1.5 Age-Related Hair Pigmentation Variations; 1.6 Hair Loss: An Aging Event?
1.7 ConclusionsReferences; 157326_1_En_2_Chapter_OnlinePDF.pdf; 2; Molecular Basis of Androgenetic Alopecia; 2.1 Introduction; 2.1.1 Patterns of Hair Loss; 2.1.1.1 In Men; 2.1.1.2 In Women; 2.1.2 Incidence; 2.1.3 Significance of Androgenetic Alopecia; 2.2 Changes During Androgenetic Alopecia; 2.2.1 Altering the Type of Hair Produced Via the Hair Follicle Growth Cycle; 2.2.2 The Miniaturisation Processes; 2.3 The Pathogenesis of Androgenetic Alopecia; 2.3.1 Seasonal Changes in Human Hair Growth; 2.3.2 Paradoxical Effects of Androgens on Human Hair Growth
2.3.3 Essential Requirement for Androgens2.3.4 Genetic Influences; 2.3.4.1 Incidence; 2.3.4.2 Investigation of Specific Genes; 2.4 Current Model for Androgen Action in the Hair Follicle; 2.5 Treatment; 2.5.1 Surgery; 2.5.2 Hormonal Treatments; 2.5.2.1 Anti-Androgens; 2.5.2.2.5 a-Reductase Inhibitors; 2.5.2.3 Non-Hormonal Therapy; 2.5.3 Future Developments; References; 157326_1_En_3_Chapter_OnlinePDF.pdf; 3; Inflammatory Phenomena and Fibrosis in Androgenetic Alopecia; 3.1 Pathobiology of Androgenetic Alopecia and Current Pharmacologic Treatment
3.2 Hair Follicle Microinflammation and Fibrosis3.3 Red Scalp; 3.4 Fibrosing Alopecia in a Pattern Distribution; 3.5 Targeting the Inflammatory Component in Androgenetic Alopecia; References; 157326_1_En_4_Chapter_OnlinePDF.pdf; 4; Post-Menopausal Frontal Fibrosing Alopecia; 4.1 Background; 4.2 Clinical Features; 4.3 Histopathological Features; 4.4 Laboratory Investigations; 4.5 Differential Diagnoses; 4.5.1 Genetically High Frontal Hairline; 4.5.2 Androgenetic Alopecia; 4.5.3 Alopecia Areata; 4.5.4 Lupus Erythematosus; 4.5.5 Traction Alopecia; 4.6 Management
4.7 PFFA and the Ageing Follicles4.7.1 Senescent Alopecia and PFFA; 4.7.2 Androgenetic Alopecia and PFFA; 4.7.3 Fibrosing Alopecia and Pattern Hair Loss; 4.7.4 PFFA and Pattern Hair Loss; 4.8 Conclusions; References; 157326_1_En_5_Chapter_OnlinePDF.pdf; 5; Female Pattern Hair Loss; 5.1 Introduction; 5.2 Clinical Features; 5.3 Prevalence; 5.4 Pathology; 5.5 Etiology; 5.5.1 Age; 5.5.2 Androgens; 5.5.3 Genetics; 5.6 Management; 5.6.1 Diagnosis; 5.6.2 Investigation; 5.6.3 Treatment; 5.6.3.1 Minoxidil; 5.6.3.2 Antiandrogens; 5.6.3.3 Surgery; 5.6.3.4 Cosmesis; 5.7 Summary; References
157326_1_En_6_Chapter_OnlinePDF.pdf

Contributor: Trüeb, Ralph M. [Author]; Tobin, Desmond J. [Other]

Published: Berlin, Heidelberg: Springer Berlin Heidelberg, 2010

Extent: Online-Ressource (XVI, 270p. 85 illus., 73 illus. in color, digital)

Language: English

DOI: 10.1007/978-3-642-02636-2

ISBN: 9783642026362

Identifier:

RVK notation: YF 4725 : Im höheren Alter

Keywords: Haar > Altern
Alopecia
Haar > Alter

Origination:

Footnote: Includes bibliographical references and index

Description: The scalp and hair are subject to both intrinsic or physiologic aging and extrinsic or premature aging caused by external factors. This comprehensive and reader-friendly book offers an up-to-date overview on all aspects of hair aging, including in particular the two main streams of interest: the aesthetic problem, which relates to everything that happens outside the skin, and the biologic problem, which concerns the "secret life" of the hair follicle in the depth of the skin. Internationally recognized experts provide detailed contributions on the biologic basis of hair aging and current concepts for its diagnosis, treatment, and prevention. The intrinsic and extrinsic modulating factors for hair growth and pigmentation are explained and future directions for therapeutic intervention are examined. In summary, this unique book offers valuable insights into hair aging and guidance on its treatment, it will prove invaluable both to dermatologists and to other interested physicians and basic scientists. TOC:Gerontobiology of the Hair Follicle.- Molecular Basis, Inflammatory Phenomena and Fibrosis of Androgenetic Alopecia.- Postmenopausal Frontal Fibrosing Alopecia.- Female Pattern Hair Loss.- Comparative Histopathology of Androgenetic Alopecia and Senescent Alopecia.- The Aging Hair Pigmentary Unit.- Mechanisms of Melanocyte Stem Cell Maintenance and Hair Graying.- Oxidative Stress Associated Melanocyte-Loss and Hair Growth Capacity.- Human Hair Follicle and Epidermal Melanocytes as a Proxy Cell Type in Neurodegeneration Research.- Effect of UV Radiation on Scalp and Hair Growth.- Hair Photoaging.- Effect of Tobacco Smoking.- Age-related General Problems.- Aging of Scalp and Age-related Disorders.- Care of Aging Hair and Photoprotection.- Possibilities and Limitations for Reversal of Hair Graying and Age Related Hair Loss.- Evidence-based Hair Transplantation.- Future Directions: Gene Polymorphism Diagnostics Relevant to Hair, Follicular Targeted Gene Therapy, Hair Follicle Stem Cells and Tissue Engineering.- Hair after Death.

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