• Media type: E-Book
  • Title: Chirality in drug research
  • Contributor: Francotte, Eric [Other]; Lindner, W. [Other]
  • imprint: Weinheim: Wiley-VCH, ©2006
    Online-Ausg.
  • Published in: Methods and principles in medicinal chemistry ; v. 33
  • Extent: Online Ressource (xix, 351 pages); illustrations
  • Language: English
  • ISBN: 9783527609437; 3527609431; 9783527608713; 3527608710; 1281087874; 9781281087874
  • RVK notation: VS 5350 : Allgemeines
  • Keywords: Chiralität > Arzneimitteldesign
  • Type of reproduction: Online-Ausg.
  • Origination:
  • Footnote: Includes bibliographical references and index. - Print version record
  • Description: Divided into the three main sections of synthesis, analysis and drug development, this handbook covers all stages of the drug development process, including large-scale synthesis and purification of chirally pure pharmaceuticals. The two editors from academia and a major pharmaceutical company have assembled an experienced, international team who provide first-hand practical advice and report previously unpublished data. In the first section, the isolation of chiral drugs from natural sources, their production in enzymatic processes and the resolution of racemic mixtures in preparative chromat