• Media type: E-Book
  • Title: Adult Stem Cells in Aging, Diseases and Cancer
  • Contains: Speakers at the symposiumStem cells in adult intestine / Feng, J., Sperka, T.
    Molecular mechanisms of muscle stem cell aging / Schwërer, S., Tümpel, S.
    Mechanism of functional alterations in hematopoietic stem cell aging / Morita, Y.
    The microenvironment, aging, and disease / Geiger, H.
    Sestrins in aging and metabolism / Tang, D., Tao S.
    Telomeres and stem cell aging / Felix, D.A.
    DNA damage and checkpoint responses in adult stem cells / Romanov, V., Shukla, A., Ju, Z.
  • Contributor: Rudolph, K. [Author]
  • imprint: Basel; New York: Karger, 2015
    2015
  • Published in: Else Kröner-Fresenius Symposia ; Vol.5
  • Extent: Online-Ressource (VIII + 88); 19
  • Language: English
  • ISBN: 9783318027327
  • Keywords: Cancer Genetic aspects Congresses ; Medical genetics Congresses ; Stem cells Congresses ; DNA Damage physiology Congresses ; Neoplasms genetics Congresses ; Adult Stem Cells physiology Congresses ; Cell Aging physiology Congresses ; genetics Congresses ; Cell Biology ; Gerontology / Geriatrics ; Molecular Biology ; Oncology ; Dermatology ; Gastroenterology ; Hematology ; Immunology ; Metabolism ; Musculoskeletal System ; Stem Cell Research ; Tissue Engineering
  • Origination:
  • Footnote: Novel understanding and cutting-edge information on adult stem cell aging
  • Description: The functionality of adult tissue stem cells from various organ systems declines during aging. This publication summarizes novel molecular mechanisms responsible for the development of aging-associated deficiencies as discussed by leading experts during the 5th Else Kröner-Fresenius Symposium. It is the first book that explicitly focuses on molecular mechanisms of stem cell aging and its consequences for disease and cancer development including both cell-intrinsic mechanisms as well as aging-induced alterations in the stem cell niche and the systemic environment.Cutting-edge information on stem cells, aging, cancer, and disease make this publication of special interest to basic researchers in the respective fields. Further, it is also intended for medical doctors in the fields of geriatrics, internal medicine, and cancer as it provides a novel understanding of the evolution of tissue dysfunction, diseases and cancer as a consequence of aging.