University thesis:
Dissertation, Georg-August-Universität Göttingen, 2020
Footnote:
Description:
Graft-derived cell-free DNA (GcfDNA) is a promising non-invasive organ integrity biomarker. In a prospective, observational, multicenter trial plasma GcfDNA was investigated in 115 adults post liver transplantation (LTx) at three German transplant centers. GcfDNA was highly elevated (>50%) on day one post-LTx, presumably due to ischemia/reperfusion damage, but rapidly decreased in patients without graft injury within 7 to 10 days to a median 50%) on day one post-LTx, presumably due to ischemia/reperfusion damage, but rapidly decreased in patients without graft injury within 7 to 10 days to a median ...