University thesis:
Dissertation, Georg-August-Universität Göttingen, 2020
Footnote:
Kumulative Arbeit
Description:
Traditional methods for phylogeny reconstruction are based on multiple sequence alignments and character-based methods. This combination of computationally expensive methods leads to very accurate results, but it is ill-suited to handle the enormous amount of sequence data that is available today. As a consequence, very fast alignment-free methods have been developed. These methods calculate pairwise distances in order to build phylogenetic trees. However, current alignment-free methods are generally less accurate than traditional methods. In this thesis, I developed Multi-SpaM which is a n...