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Media type:
E-Book;
Thesis
Title:
Assoziationen zwischen der Plasmachemerinkonzentration und verschiedenen inflammatorischen, metabolischen, renalen und kardiovaskulären Phänotypen
:
eine umfassende Untersuchung in der allgemeinen Bevölkerung
Chemerin is an adipokine that is expressed by adipose tissue and plays an important role in the fat metabolism. The aim of the present study was to analyse the associations between plasma chemerin concentrations and a broad range of different inflammatory, metabolic, renal, and cardiovascular parameters in a large population-based sample. Linear and logistic regression models were used to analyse data from 4420 subjects of the Study of Health in Pomerania (SHIP-Trend). In summary, the presented results show that chemerin is, independently of individual differences in the fat mass, associated with a number of different inflammatory, metabolic, renal, and cardiovascular parameters. Accordingly, it can be assumed that chemerin might influence important inflammatory and metabolic processes and therefore, might contribute independently to its associated diseases.