Wenleder, Stefan Hans Peter
[Author]
;
Schön, Margarete
[Degree supervisor];
Griesinger, Frank
[Degree supervisor];
Rieken, Stefan
[Degree supervisor]
CHALLENGE-Studie: Morphometrisches Tumoransprechen in Korrelation mit bildgebenden Verfahren (Spiral-CT und PET) bei Patienten mit NSCLC IIIA/B unter Induktionstherapie
= CHALLENGE Trial: Morphometric tumor response correlated with imaging (CT and PET-scan) in induction therapy in patients with NSCLC IIIA/B
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Media type:
E-Book;
Thesis
Title:
CHALLENGE-Studie: Morphometrisches Tumoransprechen in Korrelation mit bildgebenden Verfahren (Spiral-CT und PET) bei Patienten mit NSCLC IIIA/B unter Induktionstherapie
Parallel title:
CHALLENGE Trial: Morphometric tumor response correlated with imaging (CT and PET-scan) in induction therapy in patients with NSCLC IIIA/B
University thesis:
Dissertation, Georg-August-Universität Göttingen, 2021
Footnote:
Description:
CHALLENGE Trial: Morphometric tumor response correlated with imaging (CT and PET-scan) in induction therapy in patients with NSCLC IIIA/B. Introduction: In 2004 we started a phase II trial with induction therapy platinum/gemcitabine based chemotherapy and the tyrosine kinase inhibitor erlotinib in unselected subjects with the aim to identify molecular markers for a response to this regime. Methods: The study was a prospective, multi-center, open label, exploratory phase II trial to find with morphometry the pathological response rate (pRR). The subjects received an induction therapy with er...