Published:
[Erscheinungsort nicht ermittelbar]: [Verlag nicht ermittelbar], 2011
Language:
English
Origination:
University thesis:
Dissertation, 2011
Footnote:
Description:
Over the last few decades clinical cancer research has developed at accelerating speed, resulting in a tremendous increase of knowledge with regard to tumour biology, hypotheses to interfere with tumour growth and the subsequent development of anticancer therapies. Obviously, the ultimate aim of cancer research is to identify treatment approaches improving overall survival with a good quality of life. Novel anticancer therapies mostly arise from scientifi c insights in preclinical studies, and provided that they have looked promising in vitro and in animal models, at one point they have to be tested in humans. Testing new cancer therapies in patients occurs in diff erent stages, i.e. successively in phase I, phase II and phase III trials.