Description:
Seven new acylated C-glycosylflavones, Oreocharioside A-G, together with two known compounds were isolated from the whole plant of Oreocharis auricula . Their structures were characterized by the comprehensive analysis of their NMR, IR, UV, CD spectra and HRESIMS data. All the new compounds were evaluated for the antioxidant and anti-inflammatory activities. The results showed that compound 1 and 2 had significant DPPH and ABTS radical scavenging activities, with the IC 50 values of 0.32~3.20 μg/mL. Compound 2 and 3 exhibited the higher potency among all the new compounds in reducing TNF-α production