Menabbawy, Ahmed Al
[Author]
;
Schroeder, Henry
[Degree supervisor];
Flöel, Agnes
[Degree supervisor];
Usichenko, Taras I.
[Degree supervisor]Universität Greifswald
A multivariable prediction model for recovery patterns and time course of symptoms improvement in hemifacial spasm following microvascular decompression
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Media type:
E-Book;
Thesis
Title:
A multivariable prediction model for recovery patterns and time course of symptoms improvement in hemifacial spasm following microvascular decompression
University thesis:
Dissertation, Universitätsmedizin der Universität Greifswald, 2022
Footnote:
Literaturverzeichnis: Seite 22-25. - Literaturangaben
Description:
Microvascular decompression, hemifacial spasm, delayed recovery, time course of recovery
Background: Microvascular decompression (MVD) success rates exceed 90% in hemifacial spasm (HFS). However, postoperative recovery patterns and durations are variable. Objective: We aim to study factors that might influence the postoperative patterns and duration needed until final recovery. Method: Only patients following de-novo MVD with a minimum follow-up of 6 months were included. Overall trend of recovery was modeled. Patients were grouped according to recognizable clinical recovery patterns. Uni- and multivariable analyses were used to identify the factors affecting allocation to the identified patterns and time needed to final recovery. Results: 323(92.6%) patients had >90% symptom improvement and 269(77.1%) patients had complete resolution at the last follow–up. The overall trend of recovery showed steep remission within the first 6 months, followed by relapse peaking around 8 months with a second remission ~16 months. Five main recovery patterns were identified. Patterns analysis showed that evident proximal indentation of the facial nerve at REZ, males and facial palsy are associated with earlier recovery at multivariable and univariable levels. AICA, AICA/VA compressions and shorter disease durations are related to immediate resolution of the symptoms only on the univariable level. Time analysis showed that proximal indentation (vs. distal indentation), males and facial palsy witnessed significantly earlier recoveries. Conclusion: Our main finding is that in ...