University thesis:
Dissertation, Georg-August-Universität Göttingen, 2022
Footnote:
Description:
The body is constantly confronted with environmental threats and sometimes the entry of pathogens leads to severe inflammatory conditions such as sepsis or acute lung injury (ALI). Both diseases are characterized by a dysregulated immune system, which compromises homeostasis and induces multiple organ failure, thus being potentially lethal. While pathophysiological changes in ALI are mostly confined to the lung, sepsis is an example of a systemic inflammation affecting different organs including spleen, liver and lung. GCs are used in both conditionsto reduce the so called “cytokine storm”,...