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Wessels, Frederik [Author]; Lenhart, Maximilian [Author]; Neuberger, Manuel [Author]; Mühlbauer, Julia [Author]; Huber, Johannes [Author]; Breyer, Johannes [Author]; Nuhn, Philipp [Author]; Michel, Maurice Stephan [Author]; Koenig, Julian [Author]; Kriegmair, Maximilian [Author]

Validation of a German translation of the CARE questionnaire and its implementation as electronic PROM to assess patient-reported postoperative convalescence and recovery after major urological surgery

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  • Media type: E-Article
  • Title: Validation of a German translation of the CARE questionnaire and its implementation as electronic PROM to assess patient-reported postoperative convalescence and recovery after major urological surgery
  • Contributor: Wessels, Frederik [VerfasserIn]; Lenhart, Maximilian [VerfasserIn]; Neuberger, Manuel [VerfasserIn]; Mühlbauer, Julia [VerfasserIn]; Huber, Johannes [VerfasserIn]; Breyer, Johannes [VerfasserIn]; Nuhn, Philipp [VerfasserIn]; Michel, Maurice Stephan [VerfasserIn]; Koenig, Julian [VerfasserIn]; Kriegmair, Maximilian [VerfasserIn]
  • imprint: 8 May 2021
  • Published in: World journal of urology ; 39(2021), 10, Seite 3979-3991
  • Language: English
  • DOI: 10.1007/s00345-021-03713-6
  • ISSN: 1433-8726
  • Identifier:
  • Origination:
  • Footnote:
  • Description: Purpose  To validate a German translation of the convalescence and recovery evaluation (CARE) as an electronic patientreported outcome measure (ePROM) and use it to assess recovery after major urological surgery. - Methods  The CARE questionnaire was provided to patients scheduled for major urological surgery preoperatively, at discharge and 6 weeks postoperatively, using an ePROM system. Cronbach’s alpha, inter-scale correlations and confirmatory factor analysis (CFA) were used to validate the translation. Mixed linear regression models were used to identify factors influencing CARE results, and a multivariable logistic regression analysis was done to determine the predictive value of CARE results on quality of life (QoL). - Results  A total of 283 patients undergoing prostatectomy (n = 146, 51%), partial/radical nephrectomy (n = 70, 25%) or cystectomy (n = 67, 24%) responded to the survey. Internal consistency was high (α = 0.649-0.920) and the CFA showed a factor loading > 0.5 in 17/27 items. Significant main effects were found for the time of survey and type of surgery, while a time by type interaction was only found for the gastrointestinal subscale ( (24) = 30.37, p < 0.0001) and the total CARE score (TCS) ( (24) = 13.47, p = 0.009) for cystectomy patients, meaning a greater score decrease at discharge and lower level of recovery at follow-up. Complications demonstrated a significant negative effect on the TCS ( (22) = 8.61, p = 0.014). A high TCS at discharge was an independent predictor of a high QLQ-C30 QoL score at follow-up (OR = 5.26, 95%-CI 1.42-19.37, p = 0.013). - Conclusion  This German translation of the CARE can serve as a valid ePROM to measure recovery and predict QoL after major urological surgery.
  • Access State: Open Access