University thesis:
Dissertation, Georg-August-Universität Göttingen, 2024
Footnote:
Description:
Type 2 diabetes mellitus has become the most common cause of kidney failure in Europe and the United States. In Germany, 8.7 million people live with type 2 diabetes, although an estimated two million more affected people have not yet been diagnosed. Approximately 10–50% of all type 2 diabetes patients develop kidney involvement after a disease duration of 15–30 years. Long-term diabetes often leads to micro- and macrovascular impairment, leading to clinical complications in various organs such as retinopathy, cardiomyopathy, and nephropathy. Diabetic nephropathy (DN) is characterized by ex...