• Media type: E-Article
  • Title: Assessing long-term, vestibulotoxic side effects after gentamicin therapy in neonatal sepsis or infection using video head impulse test
  • Contributor: Zaubitzer, Lena [VerfasserIn]; Kotzur, Anja [VerfasserIn]; Hegemann, Stefan [VerfasserIn]; Rotter, Nicole [VerfasserIn]; Schell, Angela [VerfasserIn]
  • imprint: 26 February 2024
  • Published in: Frontiers in Pediatrics ; 12(2024) vom: Feb., Artikel-ID 1366074, Seite 1-17
  • Language: English
  • DOI: 10.3389/fped.2024.1366074
  • ISSN: 2296-2360
  • Identifier:
  • Keywords: Children ; gain ; Gentamicin ; Newborn ; refixational saccades ; Sepsis ; Vestibulotoxicity ; Video head impulse test
  • Origination:
  • Footnote:
  • Description: Question: Does gentamicin therapy in children with neonatal sepsis or infection lead to persistent vestibulotoxicity? Findings: In a single-center, prospective cross-sectional study video head impulse test (VHIT) was performed to evaluate vestibular function in 23 children aged 3-7 years at least three years after intravenous gentamicin therapy for neonatal sepsis or infection.Although eleven children showed abnormal results in vestibular testing, they did not present with a clinically significant vestibular hypofunction or delayed motoric development.VHIT can serve as a sensitive investigation method for the screening of posttherapeutic vestibulotoxic side effects after gentamicin therapy in children.
  • Access State: Open Access