Gray matter covariations and core symptoms of autism: the EU-AIMS Longitudinal European Autism Project

Media type: E-Article

Title: Gray matter covariations and core symptoms of autism : the EU-AIMS Longitudinal European Autism Project

Contributor: Mei, Ting [Author]; Llera, Alberto [Author]; Floris, Dorothea L. [Author]; Forde, Natalie J. [Author]; Tillmann, Julian [Author]; Durston, Sarah [Author]; Mößnang, Carolin Ulrike [Author]; Banaschewski, Tobias [Author]; Holt, Rosemary J. [Author]; Baron-Cohen, Simon [Author]; Rausch, Annika [Author]; Loth, Eva [Author]; Dell’Acqua, Flavio [Author]; Charman, Tony [Author]; Murphy, Declan G. M. [Author]; Ecker, Christine [Author]; Beckmann, Christian F. [Author]; Buitelaar, Jan K. [Author]

Published: 2020

Language: English

DOI: 10.1186/s13229-020-00389-4

Identifier:

Keywords: Autism ; Canonical correlation analysis ; Independent component analysis ; Magnetic resonance imaging ; Voxel-based morphometry

Origination:

Footnote:

Description: Voxel-based morphometry (VBM) studies in autism spectrum disorder (autism) have yielded diverging results. This might partly be attributed to structural alterations being associating with the combined influence of several regions rather than with a single region. Further, these structural covariation differences may relate to continuous measures of autism rather than with categorical case-control contrasts. The current study aimed to identify structural covariation alterations in autism, and assessed canonical correlations between brain covariation patterns and core autism symptoms.

Access State: Open Access

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