Description:
This book gives an updated review of the state of the art in regenerative cell therapy in the fields of cardiology, hematology, pediatrics, neurology, orthopedics and infectious diseases. The book emphasisesclinical advances as proof of concept in cell therapy based on the revolutionizing observation that regeneration can occur throughout the body even in highly differentiated organs like the heart and the neuronal system. It provides examplesofbreakthroughs in the clinical implementaion of adult stem cell therapy. TOC:G.Cossu: Problems and Hopes with Cell Therapy: The Case of Muscular Dystrophy; Ph. Menasché: Cardiac Myoblasts; Ch. Koh, A. Atala: Tissue Engineering, Stem Cells and Cloning: Current Concepts and Future Trends; Horwitz et al: Bone Marrow Cell Therapy for Genetic Disorders of Bone; M. Schwartz: Immune-based Therapy for Acute and Chronic Neurodegenerative Disorders; L.Foulliard: Mesenchymal Stem Cells for the Treatment of Hematological Malignancies: Role in Hematopoietic Stem Cell Transplantation and Bone Marrow Failure; L. Douay: Perspectives in Transfusion Medicine for the Ex Vivo Control of Hematopoiesis; M. Brenner et al.: T-Cell Therapies for EBV Associated Malignancies; D. Kurbegov, J. J. Molldrem: Peptide Vaccination of Myeloid Leukemia; M.L. Sorror, R. Storb: Hematopoietic Cell Transplantation After Nonmyeloablative Conditioning