Description:
The hedgehog signalling pathway is a highly conserved key regulator of animal development and required for homeostasis of adult tissues both in invertebrates and vertebrates. In addition, a large number of studies have suggested that this pathway is also implicated in different aspects of vertebrate haematopoiesis and lymphopoiesis. Its precise role in this context however appears to be complex and conflicting data reported from different groups have prevented a comprehensive understanding of its implication. The aim of the study at hand was to further improve the understanding of Hh signal...