Description:
Neuropsychiatric disorders, such as autism spectrum disorders (ASD), schizophrenia, anxiety disorders, major depression and substance use disorders are highly prevalent and contribute to disease burden worldwide. Accumulating evidence consistently suggest neuropsychiatric conditions as results of complex interactions between multiple genetic factors and environmental factors. However, despite large research efforts, the exact neurobiological mechanisms of neuropsychiatric disorders remain largely unknown. The present cumulative thesis has been prepared on the basis of a translational neuros...