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Dzementsei, Aliaksandr [Author] ; Pieler, Thomas [Degree supervisor]; Pieler, Thomas [Other]; Wodarz, Andreas [Other]; Kessel, Michael [Other]; Janshoff, Andreas [Other]; Dosch, Roland [Other]; Halyna, Shcherbata [Other]

Role of cellular dynamics, adhesion and polarity in the context of primordial germ cell migration in Xenopus laevis embryos

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  • Media type: E-Book; Thesis
  • Title: Role of cellular dynamics, adhesion and polarity in the context of primordial germ cell migration in Xenopus laevis embryos
  • Contributor: Dzementsei, Aliaksandr [Author]; Pieler, Thomas [Betreuer]; Wodarz, Andreas [Gutachter]; Kessel, Michael [Gutachter]; Janshoff, Andreas [Gutachter]; Dosch, Roland [Gutachter]; Halyna, Shcherbata [Gutachter]
  • imprint: 2013
  • Extent: Online-Ressource (PDF-Datei: 5,1 MB)
  • Language: English
  • Identifier:
  • Keywords: Hochschulschrift
  • Origination:
  • University thesis: Göttingen, Univ., Diss., 2013
  • Footnote:
  • Description: Directional cell migration is an intensively studied process relevant for both normal development of an organism as well as for a number of pathological conditions such as chronic inflammation and cancer. Primordial germ cells (PGCs) in Xenopus laevis embryos can be used as a model system to study cell migration, since during embryogenesis they actively migrate within the endoderm towards genital ridges. Transition to active cell migration is a highly regulated process important for the normal PGC development in many species. This study is focused on molecular and cellular mechanisms involv...
  • Access State: Open Access