Brockmeyer, Phillipp
[Author]
;
Hemmerlein, Bernhard
[Degree supervisor];
Hemmerlein, Bernhard
[Other];
Rödel, Ralph
[Other]
Connexine als potenzielle Biomarker für den Progress oraler Plattenepithelkarzinome: Analyse der Expressionsmuster von Connexin 26, 43 und 45 und ihres Einflusses auf das Überleben
You can manage bookmarks using lists, please log in to your user account for this.
Media type:
E-Book;
Thesis
Title:
Connexine als potenzielle Biomarker für den Progress oraler Plattenepithelkarzinome: Analyse der Expressionsmuster von Connexin 26, 43 und 45 und ihres Einflusses auf das Überleben
Other titles:
Connexins as potential biomarkers for the progression of oral squamous cell carcinoma: analysis of the expression pattern of connexin 26, 43 and 45 and their influence on survival
Description:
The aim of the present study was to evaluate the expression and localization of connexin (Cx) 26, -43 and -45 in a group of 35 patients with primary oral squamous cell carcinoma (OSCC) with the objective of making a more accurate disease prognosis. We analysed the expression of connexins in tissue samples of primary OSCC, matching oral mucosa free of dysplasia, and it's associated lymph node metastases (LNM) by semiquantitative immunohistochemistry of membrane, cytoplasmic and nuclear connexin expression. The level of expression was correlated with the overall survival time (OS). Cx43 was o...