You can manage bookmarks using lists, please log in to your user account for this.
Media type:
Book
Title:
Next-generation DNA sequencing informatics
Contains:
1. Introduction to DNA Sequencing
/ Stuart M. Brown
2. Quality Control and Data Preprocessing
/ Stuart M. Brown
3. History of Sequencing Informatics
/ Stuart M. Brown
4. Public Sequence Databases ; Stuart M. Brown ; 5. Visualization of Next-Generation Sequencing Data
/ Philip Ross Smith, Kranti Konganti, and Stuart M. Brown
6. DNA Sequence Alignment
/ Efstratios Efstathiadis
7. Genome Assembly Using Generalized de Bruijin Digraphs
/ D. Frank Hsu
8. De novo Assembly of Bacterial Genomes from Short Sequence Reads
/ Silvia Argimón and Stuart M. Brown / 9. De novo Transcriptome Assembly / Lisa Cohen, Steven Shen, and Efstratios Efstathiadis
10. Genome Annotation
/ Steven Shen and Stuart M. Brown
11. Using Next-Generation Sequencing to Detect Sequence Variants
/ Jinhua Wang, Zuojian Tang, and Stuart M. Brown
12. ChIP-seq ; Stuart M. Brown, Zuojian Tang, Christina Schweikert, and D. Frank Hsu ; 13. RNA Sequencing with Next-Generation Sequencing
/ Stuart M. Brown and Jeremy Goecks
14. Metagenomics
/ Guillermo I. Perez-Perez, Miroslav Blumenberg, and Alexander V. Alekseyenko
15. Proteogenomics
/ Kelly V. Ruggles and David Fenyö
16. Emerging DNA Sequencing Technologies and Applications
/ Gerald A. Higgins and Brian D. Athey
17. Cloud-based Next-Generation Sequencing Informatics
/ Konstantinos Krampis, Efstratios Efstathiadis, and Stuart M. Brown
Glossary ; Index.
"Next-generation DNA sequencing (NGS) technology has revolutionized biomedical research, making genome and RNA sequencing an affordable and frequently used tool for a wide variety of research applications including variant (mutation) discovery, gene expression, transcription factor analysis, metagenomics, and epigenetics. Bioinformatics methods to support DNA sequencing have become and remain a critical bottleneck for many researchers and organizations wishing to make use of NGS technology. Next-Generation DNA Sequencing Bioinformatics, Second Edition, provides thorough, plain language introduction to the necessary informatics methods and tools for analyzing NGS data as did the first edition, and provides detailed descriptions of algorithms, strengths and weaknesses of specific tools, pitfalls and alternative methods. Four new chapters in this edition cover: experimental design, sample preparation, and quality assessment of NGS data; Public databases for DNA Sequencing data; De novo transcript assembly; proteogenomics; and emerging sequencing technologies. The remaining chapters from the first edition have been updated with the latest information. This book also provides extensive reference to best-practice bioinformatics methods for NGS applications and tutorials for common workflows. The second edition of Next-Generation DNA Sequencing Bioinformatics addresses the informatics needs of students, laboratory scientists, and computing specialists who wish to take advantage of the explosion of research opportunities offered by new DNA sequencing technologies"--
"Next-generation DNA sequencing (NGS) technology has revolutionized biomedical research, making complete genome sequencing an affordable and frequently used tool for a wide variety of research applications. This book provides a thorough introduction to the necessary informatics methods and tools for operating NGS instruments and analyzing NGS data"--