Description:
The most widely used animal model for biomedical research is the mouse. Yet, the physiological differences between mice and humans sometimes result in findings of questionable translational value. The common marmoset monkey (Callithrix jacchus) is a non-human primate, which is gaining more and more interest as a translational model organism. However, methods for the genetic modification, which have been well-established in the mouse for decades, have only recently become available for the common marmoset. In this study I applied different tools for transgenesis and targeted gene modificatio...