University thesis:
Rostock, Univ., Mathematisch-Naturwiss. Fak., Diss., 2015
Footnote:
Description:
This thesis includes regioselective palladium catalyzed Suzuki-Miyaura cross coupling reactions of isatins benzoxazols isoflavones and coumarins. These classes of compounds are of pharmacological relevance. Suzuki-Miyaura cross-coupling reactions of dichloro methylindolinen dione afforded arylated isatins. The reactions proceeded with very good site selectivity. The Suzuki-Miyaura reaction of dichlorobenzoxazol, of the bis(triflate) of dihydroxyisoflavone, and of the bis(triflate) of methyl dihydroxycoumarin, with different boronic acids, gave the corresponding site-selective mono-arylated, homo bis-arylated and mixed bis-arylated derivaties, most of them with very good site-selectivity.