Description:
Osteoporosis-induced bone fractures and their delayed healing are a frequent and worldwide problem. Thus, safe and non-pharmacological methods for enhancing poor healing tendency in osteoporotic bones are of high medical interest. In this experiment the effect of mechanical stimulation (vertical Whole-Body Vibration) on metaphyseal tibial bone healing in intact and ovariectomized rats was investigated. Half of 60 female Sprague-Dawley rats were ovariectomized at the age of three months. Ten weeks later all rats underwent bilateral metaphyseal osteotomy of tibia. Five days after the osteotom...