University thesis:
Dissertation, Albert-Ludwigs-Universität Freiburg i. Br., 2016
Footnote:
Description:
Zusammenfassung: Background: The Deep Inferior Epigastric Perforator (DIEP)-flap is nowadays a common approach for breast reconstruction in breast cancer patients after mastectomy. Fat-grafting to optimize the aesthetic outcome often follows the reconstruction. Although lipofilling is widely used in this field, there is still no clear consensus on its oncological safety. Furthermore certain patients have additional personal risk factors (e.g. high grade tumor) that could potentially work in synergy with the lipo-aspirate and increase the risk of cancer recurrence. Therefore it is crucial to improve patient selection for fat grafting procedures. This study identifies potential risk factors to improve patient selection for lipofilling procedures.Material&Methods:Matched cohort study- The survival rate of 100 patients that underwent lipofilling after their DIEP-flap reconstruction was compared retrospectively with 100 matched control patients that did not undergo lipofilling after their flap surgery. Both groups had no recurrence between their mastectomy and lipofilling, the latter labeled as the “startpoint” of the survival follow-up