• Media type: Text; Report; E-Book
  • Title: Optimal distributed control of a Cahn-Hilliard-Darcy system with mass sources
  • Contributor: Sprekels, Jürgen [Author]; Wu, Hao [Author]
  • Published: Berlin : Weierstraß-Institut für Angewandte Analysis und Stochastik, 2018
  • Issue: published Version
  • Language: English
  • DOI: https://doi.org/10.34657/2918; https://doi.org/10.20347/WIAS.PREPRINT.2548
  • ISSN: 0946-8633; 2198-5855
  • Keywords: Cahn–Hilliard–Darcy system ; necessary optimality condition ; distributed optimal control
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  • Description: In this paper, we study an optimal control problem for a two-dimensional CahnHilliardDarcy system with mass sources that arises in the modeling of tumor growth. The aim is to monitor the tumor fraction in a finite time interval in such a way that both the tumor fraction, measured in terms of a tracking type cost functional, is kept under control and minimal harm is inflicted to the patient by administering the control, which could either be a drug or nutrition. We first prove that the optimal control problem admits a solution. Then we show that the control-to-state operator is Fréchet differentiable between suitable Banach spaces and derive the first-order necessary optimality conditions in terms of the adjoint variables and the usual variational inequality.
  • Access State: Open Access