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Höhl, Martin [Author]; Detemple, Daphne [Author]; Lyutenski, Stefan [Author]; Leuteritz, Georg [Author]; Varkentin, Arthur [Author]; Schmitt, Heike Andrea [Author]; Lenarz, Thomas [Author]; Roth, Bernhard [Author]; Meinhardt-Wollweber, Merve [Author]; Morgner, Uwe [Author]

Optical properties of the human round window membrane - [published Version]

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  • Media type: Text; E-Article
  • Title: Optical properties of the human round window membrane
  • Contributor: Höhl, Martin [Author]; Detemple, Daphne [Author]; Lyutenski, Stefan [Author]; Leuteritz, Georg [Author]; Varkentin, Arthur [Author]; Schmitt, Heike Andrea [Author]; Lenarz, Thomas [Author]; Roth, Bernhard [Author]; Meinhardt-Wollweber, Merve [Author]; Morgner, Uwe [Author]
  • imprint: Bellingham, WA : S P I E - International Society for Optical Engineering, 2017
  • Published in: Journal of Biomedical Optics 22 (2017), Nr. 10
  • Issue: published Version
  • Language: English
  • DOI: https://doi.org/10.15488/2537; https://doi.org/10.1117/1.JBO.22.10.105007
  • Keywords: Probes ; transmission ; round window membrane ; perilymph ; Visible wavelengths ; fiber optic probe ; Fiberoptic probes ; Optical properties of biological tissues ; Tissue ; Diagnosis ; Diagnostic applications ; Konferenzschrift ; Fiber optics ; Light transmission ; Transmissions ; Histology ; Noninvasive examination ; Optical properties ; Forward scattering ; Experimental methods ; Noninvasive analysis ; scattering ; Membranes ; Audition
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  • Description: Optical techniques are effective tools for diagnostic applications in medicine and are particularly attractive for the noninvasive analysis of biological tissues and fluids in vivo. Noninvasive examinations of substances via a fiber optic probe need to consider the optical properties of biological tissues obstructing the optical path. This applies to the analysis of the human perilymph, which is located behind the round window membrane. The composition of this inner ear liquid is directly correlated to inner ear hearing loss. In this work, experimental methods for studying the optical properties of the human round window membrane ex vivo are presented. For the first time, a comprehensive investigation of this tissue is performed, including optical transmission, forward scattering, and Raman scattering. The results obtained suggest the application of visible wavelengths (>400nm) for investigating the perilymph behind the round window membrane in future. © 2017 Society of Photo-Optical Instrumentation Engineers (SPIE).
  • Access State: Open Access