Kohl, S.
[Author];
Wolters, Carolin
[Author];
Gruendler, Theo O. J.
[Author];
Vogeley, Kai
[Author];
Klosterkötter, Joachim
[Author];
Kuhn, Jens
[Author]
Prepulse Inhibition of the Acoustic Startle Reflex in High Functioning Autism
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Media type:
E-Article
Title:
Prepulse Inhibition of the Acoustic Startle Reflex in High Functioning Autism
Contributor:
Kohl, S.
[Author];
Wolters, Carolin
[Author];
Gruendler, Theo O. J.
[Author];
Vogeley, Kai
[Author];
Klosterkötter, Joachim
[Author];
Kuhn, Jens
[Author]
imprint:
PLoS, 2014
Published in:PLoS one 9(3), e92372 - (2014). doi:10.1371/journal.pone.0092372
Language:
English
DOI:
https://doi.org/10.1371/journal.pone.0092372
ISSN:
1932-6203
Origination:
Footnote:
Diese Datenquelle enthält auch Bestandsnachweise, die nicht zu einem Volltext führen.
Description:
High functioning autism is an autism spectrum disorder that is characterized by deficits in social interaction and communication as well as repetitive and restrictive behavior while intelligence and general cognitive functioning are preserved. According to the weak central coherence account, individuals with autism tend to process information detail-focused at the expense of global form. This processing bias might be reflected by deficits in sensorimotor gating, a mechanism that prevents overstimulation during the transformation of sensory input into motor action. Prepulse inhibition is an operational measure of sensorimotor gating, which indicates an extensive attenuation of the startle reflex that occurs when a startling pulse is preceded by a weaker stimulus, the prepulse.