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Media type:
E-Article
Title:
Filamentous active matter: Band formation, bending, buckling, and defects
Contributor:
Vliegenthart, Gerard A.
[Author];
Ravichandran, Arvind
[Author];
Ripoll, Marisol
[Author];
Auth, Thorsten
[Author];
Gompper, Gerhard
[Author]
imprint:
Assoc., 2020
Published in:Science advances 6(30), eaaw9975 (2020). doi:10.1126/sciadv.aaw9975
Language:
English
DOI:
https://doi.org/10.1126/sciadv.aaw9975
ISSN:
2375-2548
Origination:
Footnote:
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Description:
Motor proteins drive persistent motion and self-organization of cytoskeletal filaments. However, state-of-the-art microscopy techniques and continuum modeling approaches focus on large length and time scales. Here, we perform component-based computer simulations of polar filaments and molecular motors linking microscopic interactions and activity to self-organization and dynamics from the filament level up to the mesoscopic domain level. Dynamic filament cross-linking and sliding and excluded-volume interactions promote formation of bundles at small densities and of active polar nematics at high densities. A buckling-type instability sets the size of polar domains and the density of topological defects. We predict a universal scaling of the active diffusion coefficient and the domain size with activity, and its dependence on parameters like motor concentration and filament persistence length. Our results provide a microscopic understanding of cytoplasmic streaming in cells and help to develop design strategies for novel engineered active materials.