Constitutive activity of the human histamine H4 receptor: Molecular modelling, binding and functional studies on wild-type and mutant H4R orthologs

Media type: E-Book; Thesis

Title: Constitutive activity of the human histamine H4 receptor: Molecular modelling, binding and functional studies on wild-type and mutant H4R orthologs

Other titles: Konstitutive Aktivität des humanen Histamin H4 Rezeptors: Molecular Modelling, Bindungs- und funktionelle Studien an Wild-Typ und mutierten H4R Orthologen

Contributor: Wifling, David [Author]; Buschauer, Armin [Degree supervisor]

Published: Regensburg: Universitätsbibliothek Regensburg, 2015

Extent: Online-Ressource

Language: English

Identifier:

Keywords: Arzneimittelentwicklung ; Arzneimitteldesign ; constitutive activity, Sf9 cells, ligand binding, H4 receptor, H4 receptor orthologs, histamine, site-directed mutagenesis, GTP(gamma)S binding, radioligand binding, JNJ7777120, clozapine, isoloxapine, VUF8430, immepip, clobenpropit, thioperamide, UR-PI376, UR-PI294 ; Hochschulschrift

Origination:

University thesis: Regensburg, Universität Regensburg, Diss., 2015

Footnote:

Access State: Open Access

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