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Heilmann, Romy M. [Author]; McIntosh, Jenny [Author]; Acke, Els [Author]; Reitemeier, Susanne [Author]; Pfannkuche, Helga Pfannkuche [Author]; Erdmann, Sabrina [Author]; Roedler, Frauke S. [Author]; Einspanier, Almuth [Author]

Feasibility of combined upper and lower gastrointestinal endoscopic biopsy in the common marmoset (Callithrix jacchus) to evaluate gastrointestinal diseases

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  • Media type: E-Article
  • Title: Feasibility of combined upper and lower gastrointestinal endoscopic biopsy in the common marmoset (Callithrix jacchus) to evaluate gastrointestinal diseases
  • Contributor: Heilmann, Romy M. [Author]; McIntosh, Jenny [Author]; Acke, Els [Author]; Reitemeier, Susanne [Author]; Pfannkuche, Helga Pfannkuche [Author]; Erdmann, Sabrina [Author]; Roedler, Frauke S. [Author]; Einspanier, Almuth [Author]
  • imprint: Oxford: Wiley-Blackwell, [2023]
  • Published in: Journal of medical primatology ; 51,3 (2022), Seite 172-178
  • Language: English
  • DOI: 10.1111/jmp.12580
  • Keywords: biopsy forceps ; anesthesia ; histopathology ; duodenum ; intubation ; endoscopy ; marmoset monkey
  • Origination:
  • Footnote:
  • Description: Background: Chronic gastroenteropathies, including gluten sensitivity and marmosetwasting syndrome, frequently occur in captive colonies of common marmosets(Callithrix jacchus). Early identification and diagnosis of affected animals are desirable.Endoscopic examination of the colon in marmosets is described, but the smallintestine can harbor significant mucosal lesions not representing those in the colon.Evaluating the small intestine currently requires invasive surgical biopsies due to thesmall patient size, carrying a risk of severe complications.Methods: Endoscopic intubation and multisite biopsy of the duodenum/proximal jejunumare demonstrated in 10 marmosets under general anesthesia.Results: Esophagogastroduodenoscopy with colonoscopy efficiently aid in examiningthe gastrointestinal tract and obtaining an antemortem histologic diagnosis in marmosetswith chronic gastrointestinal signs.Conclusions: This minimally invasive technique is feasible in marmosets. Future investigationsinto the pathogenesis of chronic gastroenteropathies will benefit from thesedata, leading to improved animal welfare and better individual and colony healthmanagement
  • Access State: Open Access
  • Rights information: Attribution - Non Commercial - No Derivs (CC BY-NC-ND)